SNP rs nr | Genotype | p-value for interaction | All individuals | Height <162.0 cm | Height 162.0-166.0 cm | Height >166.0 cm | ||||
---|---|---|---|---|---|---|---|---|---|---|
case/contr: 2869/4480 | case/control: 776/1366 | case/control: 967/1407 | case/control: 1023/1502 | |||||||
OR 95%CI | p-trend | OR 95%CI | p-trend | OR 95%CI | p-trend | OR 95%CI | p-trend | |||
FGFR2 2981582 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.23 (1.10-1.37) | 1.35 (1.10-1.66) | 1.33 (1.10-1.61) | 1.07 (0.89-1.28) | ||||||
aa | 1.48 (1.29-1.69) | 1.57 (1.21-2.02) | 1.56 (1.22-1.99) | 1.32 (1.04-1.67) | ||||||
Per Allele | 0,41 | 1.22 (1.14-1.30) | 1.34E-08 | 1.26 (1.11-1.43) | 2.86E-04 | 1.26 (1.12-1.42) | 1.65E-04 | 1.14 (1.01-1.28) | 0.03 | |
TNR09 3803662 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.14 (1.03-1.26) | 1.09 (0.90-1.32) | 1.23 (1.03-1.47) | 1.15 (0.97-1.36) | ||||||
aa | 1.39 (1.17-1.67) | 1.37 (1.00-1.87) | 1.37 (1.00-1.89) | 1.42 (1.03-1.95) | ||||||
Per Allele | 0,91 | 1.16 (1.08-1.25) | 5.34E-05 | 1.14 (1.00-1.31) | 0.06 | 1.20 (1.05-1.37) | 6.78E-03 | 1.17 (1.03-1.33) | 0.02 | |
MAP3K1 889312 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.21 (1.09-1.34) | 1.29 (1.06-1.55) | 1.14 (0.95-1.36) | 1.18 (1.00-1.40) | ||||||
aa | 1.29 (1.09-1.54) | 1.31 (0.95-1.81) | 1.05 (0.76-1.45) | 1.53 (1.14-2.06) | ||||||
Per Allele | 0,45 | 1.17 (1.08-1.26) | 4.26E-05 | 1.20 (1.04-1.37) | 9.92E-03 | 1.07 (0.94-1.22) | 0.29 | 1.22 (1.07-1.38) | 2.20E-03 | |
8q24 13281615 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.12 (1.00-1.24) | 1.21 (0.98-1.48) | 1.07 (0.89-1.29) | 1.12 (0.93-1.34) | ||||||
aa | 1.15 (1.00-1.32) | 1.24 (0.96-1.60) | 1.17 (0.92-1.49) | 1.09 (0.87-1.38) | ||||||
Per Allele | 0,90 | 1.08 (1.01-1.15) | 0.03 | 1.12 (0.99-1.27) | 0.07 | 1.08 (0.96-1.22) | 0.20 | 1.06 (0.94-1.18) | 0.35 | |
LSP1 3817198 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.12 (1.02-1.24) | 1.19 (0.99-1.45) | 1.08 (0.90-1.28) | 1.08 (0.91-1.28) | ||||||
aa | 1.19 (1.00-1.40) | 1.50 (1.11-2.02) | 1.14 (0.84-1.55) | 1.04 (0.79-1.38) | ||||||
Per Allele | 0,48 | 1.10 (1.02-1.18) | 8.65E-03 | 1.21 (1.06-1.39) | 4.41E-03 | 1.07 (0.94-1.22) | 0.29 | 1.04 (0.92-1.18) | 0.50 | |
2q35 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.05 (0.93-1.19) | 0.90 (0.72-1.14) | 1.21 (0.98-1.50) | 0.97 (0.79-1.19) | ||||||
aa | 1.20 (1.05-1.37) | 1.09 (0.85-1.40) | 1.28 (1.01-1.63) | 1.21 (0.96-1.52) | ||||||
Per Allele | 0,38 | 1.10 (1.03-1.17) | 7.47E-03 | 1.05 (0.93-1.19) | 0.43 | 1.13 (1.00-1.27) | 0.04 | 1.10 (0.98-1.23) | 0.11 | |
ESR1 7766585 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 1.23 (1.10-1.37) | 1.12 (0.90-1.38) | 1.26 (1.03-1.53) | 1.25 (1.04-1.50) | ||||||
aa | 1.02 (0.74-1.41) | 0.83 (0.43-1.58) | 1.21 (0.69-2.13) | 0.98 (0.57-1.66) | ||||||
Per Allele | 0,83 | 1.16 (1.05-1.27) | 2.66E-03 | 1.05 (0.88-1.26) | 0.60 | 1.20 (1.02-1.42) | 0.03 | 1.16 (0.99-1.36) | 0.06 | |
HCN1 981782 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 0.97 (0.87-1.09) | 0.92 (0.74-1.14) | 1.03 (0.84-1.26) | 1.00 (0.82-1.21) | ||||||
aa | 0.86 (0.75-0.99) | 0.91 (0.70-1.18) | 0.96 (0.75-1.22) | 0.77 (0.61-0.98) | ||||||
Per Allele | 0,51 | 0.93 (0.87-1.00) | 0.04 | 0.95 (0.83-1.08) | 0.44 | 0.98 (0.87-1.11) | 0.73 | 0.88 (0.78-0.99) | 0.04 | |
ESR1 851987 | AA | 1 | 1 | 1 | 1 | |||||
Aa | 0.91 (0.82-1.02) | 0.96 (0.78-1.17) | 0.92 (0.76-1.11) | 0.87 (0.73-1.05) | ||||||
aa | 0.88 (0.74-1.05) | 1.44 (1.06-1.95) | 0.69 (0.50-0.96) | 0.71 (0.52-0.98) | ||||||
Per Allele | 6.70E-03 | 0.93 (0.86-1.00) | 0.06 | 1.12 (0.97-1.28) | 0.12 | 0.86 (0.75-0.99) | 0.04 | 0.86 (0.75-0.98) | 0.02 |