Table 2 Observed relative risks of coronary heart disease according to estimated Your Disease Risk (YDR) relative risk category among 55,802 Nurses’ Health Study participants, 1994–2004, overall and stratified by age in 1994
From: Validation of a risk prediction tool for coronary heart disease in middle-aged women
Estimated YDR relative risk category | N (%) | No. cases (total = 1165) | Observed RR (95 % CI)a | Age–adjusted RR(95 % CI)b |
|---|---|---|---|---|
Very much below average (RR ≤ 0.2) | 23,140 (41.5) | 290 | 0.42 (0.32–0.55) | 0.43 (0.33–0.56) |
Much below average (0.2 < RR ≤ 0.5) | 14,941 (26.8) | 308 | 0.70 (0.53–0.91) | 0.68 (0.52–0.89) |
Below average (0.5 < RR ≤ 0.9) | 7278 (13.0) | 173 | 0.81 (0.61–1.07) | 0.78 (0.59–1.04) |
About average (0.9 < RR ≤ 1.1) | 2321 (4.2) | 68 | 1.00 (REF) | 1.00 (REF) |
Above average (1.1 < RR ≤ 2.1) | 4369 (7.8) | 166 | 1.31 (0.98–1.74) | 1.32 (0.99–1.76) |
Much above average (2.1 < RR ≤ 5.1) | 2836 (5.1) | 115 | 1.40 (1.03–1.90) | 1.55 (1.14–2.11) |
Very much above average (RR > 5.1) | 917 (1.6) | 45 | 1.71 (1.16–2.51) | 2.48 (1.68–3.67) |
Age < 60 (N = 27,166) | ||||
Very much below average (RR ≤ 0.2) | 11,390 (41.9) | 56 | 0.39 (0.22–0.71) | 0.40 (0.22–0.71) |
Much below average (0.2 < RR ≤ 0.5) | 6923 (25.5) | 62 | 0.72 (0.40–1.29) | 0.71 (0.40–1.28) |
Below average (0.5 < RR ≤ 0.9) | 3271 (12.0) | 38 | 0.94 (0.51–1.73) | 0.93 (0.50–1.72) |
About average (0.9 < RR ≤ 1.1) | 1129 (4.2) | 14 | 1.00 (REF) | 1.00 (REF) |
Above average (1.1 < RR ≤ 2.1) | 2156 (7.9) | 47 | 1.78 (0.97–3.24) | 1.73 (0.95–3.15) |
Much above average (2.1 < RR ≤ 5.1) | 1586 (5.8) | 40 | 2.06 (1.12–3.81) | 2.01 (1.09–3.72) |
Very much above average (RR > 5.1) | 711 (2.6) | 26 | 3.02 (1.57–5.83) | 2.97 (1.54–5.74) |
Age ≥60 (N = 28,636) | ||||
Very much below average (RR ≤ 0.2) | 11,750 (41.0) | 234 | 0.43 (0.32–0.58) | 0.43 (0.32–0.59) |
Much below average (0.2 < RR ≤ 0.5) | 8018 (28.0) | 246 | 0.67 (0.49–0.90) | 0.67 (0.50–0.91) |
Below average (0.5 < RR ≤ 0.9) | 4007 (14.0) | 135 | 0.74 (0.53–1.01) | 0.74 (0.54–1.02) |
About average (0.9 < RR ≤ 1.1) | 1192 (4.2) | 54 | 1.00 (REF) | 1.00 (REF) |
Above average (1.1 < RR ≤ 2.1) | 2213 (7.7) | 119 | 1.20 (0.86–1.67) | 1.20 (0.87–1.67) |
Much above average (2.1 < RR ≤ 5.1) | 1250 (4.4) | 75 | 1.35 (0.94–1.93) | 1.40 (0.98–2.00) |
Very much above average (RR > 5.1) | 206 (0.7) | 19 | 2.14 (1.24–3.69) | 2.27 (1.32–3.93) |