Assessing the relationship between gut microbiota and endometriosis: a bidirectional two-sample mendelian randomization analysis

Table 1 Heterogeneity and pleiotropy evaluations for genetically causal associations of gut microbiota with EMs risk

Gut microbiota	nSNP	Cochran’s Q Pval		MR-Egger		MR Steiger
Gut microbiota	nSNP	IVW	MR-Egger	egger_intercept	Pval	Direction	Pval
class Melainabacteria	10	10.645	0.329	−0.026	0.288	TRUE	1.17E−61
family Prevotellaceae	16	15.496	0.346	0.002	0.933	TRUE	6.98E−56
genus Anaerotruncus	13	13.755	0.405	0.028	0.166	TRUE	6.22E−42
genus Eubacterium ruminantium group	18	12.733	0.692	< 0.001	0.983	TRUE	5.80E−61
genus Olsenella	10	7.374	0.524	0.011	0.629	TRUE	1.16E−33
genus Oscillospira	8	3.269	0.824	0.023	0.555	TRUE	1.22E−27
order Bacillales	9	2.759	0.935	0.020	0.561	TRUE	3.45E−31

ISSN: 1472-6874