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Table 1 Study population characteristics among the breast cancer patients and healthy participants

From: High-protein diet scores, macronutrient substitution, and breast cancer risk: insights from substitution analysis

Variables

Control (n = 267)

Case (n = 134)

P-value

Demographic data

    Age (year)

47.1 ± 10.0

49.5 ± 10.7

0.035

    First pregnancy age (year)

18.2 ± 7.4

19.6 ± 8.6

0.040

    Body mass index (Kg/m2)

29.0 ± 5.4

30.1 ± 5.7

0.071

    Physical activity (MET/min/week)

32.7 ± 5.2

32.9 ± 5.4

0.701

    Menopausal status (yes, %)

42.7

53.7

0.037

    Cancer family history (yes, %)

20.6

30.6

0.028

    Anti-inflammatory drug (yes, %)

17.2

7.5

0.007

    Vitamin D supplement intake (yes, %)

24.3

14.9

0.029

    Education level (Bachelor and higher, %)

14.6

19.4

0.178

    Occupation (employed, %)

20.6

17.2

0.442

    Family size (> 4 members, %,)

55.4

56.7

0.807

    Socio economic status (%)

  

0.531

    Low (%)

37.1

38.1

 

    Middle (%)

43.8

37.3

 

    High (%)

18.7

21.6

 

Dietary intakes

   

    Energy intake (Kcal/d)

2753 ± 798

2562 ± 612

0.015

    Carbohydrate (% of energy)

53.0 ± 6.4

52.4 ± 6.1

0.437

    Refined CHO (% of energy)

23.8 ± 8.0

24.3 ± 7.8

0.584

    Non-refined CHO (% of energy)

30.9 ± 8.0

29.8 ± 8.1

0.215

    Protein (% of energy)

12.7 ± 2.1

12.4 ± 2.0

0.100

    Animal protein (% of energy)

7.0 ± 2.4

6.8 ± 2.2

0.357

    Plant protein (% of energy)

5.9 ± 1.1

5.6 ± 1.1

0.023

    Fat (% of energy)

34.3 ± 6.7

35.2 ± 6.6

0.213

    Animal fat (% of energy)

11.4 ± 4.4

11.2 ± 3.5

0.684

    Plant fat (% of energy)

19.2 ± 7.9

20.3 ± 7.5

0.171

    High protein low CHO- fat score

16.8 ± 3.8

15.9 ± 3.9

0.026

    High protein-CHO, and low-fat score

16.9 ± 6.8

15.7 ± 6.6

0.087

    High protein-fat, and low CHO score

16.5 ± 6.0

16.5 ± 5.7

0.959

  1. Data are expressed as mean ± SD and percent (%) for continuous and categorical variables, respectively
  2. CHO carbohydrate, MET metabolic equivalent