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Table 2 Main characteristics of case-only studies included in the meta-analysis

From: The association between mammographic density and breast cancer risk in Chinese women: a systematic review and meta-analysis

S.no

First author, year (ref)

Study design

Region

Adj: variables adjusted

Type of BC

Invasive or invasive and DCIS

Mammographic density categories [no/little, low, medium, high]

Age at breast cancer diagnosis

Mean (SD) or range

Breast cancer cases (n)

Quality score by MINOS

1

Li, 2017 [21]

Retrospective

Kunming

Age, menopausal status, and other variables.

Invasive breast cancer only

BI-RADSb [1 + 2,3 + 4]

22 ~ 69

69

41:28 (premenopausal: postmenopausal)

6

2

Li, 2019 [23]

Retrospective

Beijing

Age, BMI, menopausal status, parity, and other variables.

Invasive breast cancer only

BI-RADSb [1 + 2,3,4]

51.7 (10.7)

1779

889:890 (premenopausal: postmenopausal)

7

3

Zhao, 2020 [14]

Retrospective

Harbin

Not formally age-adjusted.

Invasive breast cancer only

BI-RADSa [1 + 2,3 + 4]

25 ~ 69

47 (NK)

119

68:51 (premenopausal: postmenopausal)

6

4

Ji, 2021 [26]

Retrospective

Tianjin

Age.

Both

BI-RADSb [1, 2, 3, 4]

19 ~ 93

54.3 (11.2)

9716

4892:4824 (premenopausal: postmenopausal)

6

  1. BMI Body mass index, SD Standard deviation, DCIS Ductal carcinoma in situ, BC Breast cancer
  2. aACR BI-RADS Atlas 4th edition [28]
  3. bACR BI-RADS Atlas 5th edition [29]