Table 3 Background characteristics according to whether or not participants developed docetaxel-induced systemic edema

Age (years)

54

44.5–64

48

43.5–51.8

0.109

Body mass at baseline (kg)

55.5

52.2–59

50.6

46.0–53.4

0.017*

Body fat mass at baseline (kg)

17.3

12.7–20.3

12.3

10.9–15.5

0.019*

BMI at baseline (kg/m²)

22.7

19.9–23.8

19.6

18.9–22.3

0.014*

n

%

n

%

Disease

Right breast cancer

10

40.0

8

66.6

0.103

Left breast cancer

8

32.0

4

33.4

Bilateral breast cancer

7

28.0

0

0

Purpose of the treatment

Neoadjuvant

9

36.0

6

50.0

0.484

Adjuvant

10

40.0

5

41.6

Recurrence or advanced

6

24.0

1

8.3

Disease stage

I

5

20.0

2

16.6

0.451

II

10

40.0

8

66.6

III

4

16.0

1

8.4

IV

6

24.0

1

8.4

Disease subtype

ER + /Her2 − 

13

52.0

4

33.4

0.156

ER − /Her2 + 

3

12.0

0

0

ER + /Her2 + 

9

36.0

8

66.6

Chemotherapy regimen

T

11

44.0

4

33.3

0.619

THP

10

40.0

7

58.3

TCbHP

2

8.0

1

8.4

TC

2

8.0

0

0

Her2 status

Her2 + 

12

48.0

8

66.7

0.286

Her2 − 

13

52.0

4

33.3

Menopausal status

Pre-menopausal

11

44.0

7

58.3

0.414

Post-menopausal

14

56.0

5

41.7

Smoker

Yes

4

16.0

4

33.3

0.231

No

21

84.0

8

66.7

History of alcohol consumption

Yes

10

40.0

1

16.7

0.049*

No

15

60.0

11

83.3

Use of diuretics

Yes

5

20.0

2

16.7

0.809

No

20

80.0

10

83.3

Marital status

Yes

13

52.0

6

50.0

0.909

No

12

48.0

6

50.0

In employment

Yes

10

40.0

5

41.7

0.923

No

15

60.0

7

58.3

Educational background

Junior high school

1

4.0

1

8.4

0.506

High school

8

32.0

1

8.4

College school

5

20.0

3

25.0

Undergraduate or above

10

40.0

7

58.3

No answer

1

4.0

0

0

Income

 < 2 million yen p.a

2

8.0

2

16.6

0.171

2–6 million yen p.a

8

32.0

5

41.7

 > 6 million yen p.a

3

12.0

4

33.3

No answer

12

48.0

1

8.4