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Table 2 Unadjusted and Adjusted Odds Ratio (OR) and 95% Confidence Interval (CI) for Placental Abruption in Relation to Maternal History of Headaches and Migraine, Lima, Peru, 2006-2008

From: Risk of placental abruption in relation to migraines and headaches

 

Placental Abruption

  
 

Cases (N = 375)

Controls (N = 368)

  

Exposure Status

n

%

n

%

Unadjusted

OR (95% CI)

1Adjusted

OR (95% CI)

Lifetime History of Headaches and Migraine (ICHD Criteria)

   

   No

225

60.0

259

70.4

  

   Yes

150

40.0

109

29.6

1.58 (1.17-2.15)

1.60 (1.16-2.20)

Migraine headache

44

11.7

23

6.3

2.20 (1.29-3.76)

2.14 (1.22-3.75)

Tension-type headaches

51

13.6

38

10.3

1.54 (0.98-2.44)

1.61 (1.01-2.57)

Other headaches

55

14.7

48

13.0

1.32 (0.86-2.02)

1.35 (0.87-2.09)

Lifetime History of Migraine with aura(ICHD criteria) 2

    

   No Headaches or Migraine

225

60.0

259

70.4

1.00 (referent)

1.00 (referent)

Migraine without aura

23

6.1

12

3.3

2.21 (1.07-4.53)

2.11 (1.00-4.45)

Migraine with aura

21

5.6

11

3.0

2.20 (1.04-4.66)

1.59 (0.70-3.62)

Onset of Migraine (ICHD criteria) 2

      

   No Headaches or Migraine

225

60.0

259

70.4

1.00 (referent)

1.00 (referent)

Yes, onset during pregnancy

5

1.3

2

0.5

2.88 (0.55-14.98)

2.63 (0.48-14.44)

Yes, onset prior to pregnancy

39

10.4

21

5.7

2.14 (1.22-3.74)

1.79 (0.98-3.27)

Headache or Migraine Onset

      

   No headache

225

60.0

259

70.4

1.00 (referent)

1.00 (referent)

   Final month of pregnancy

5

1.3

3

0.8

1.92 (0.45-8.12)

1.67 (0.39-7.24)

   First 8 months of pregnancy

34

9.1

24

6.5

1.63 (0.94-2.83)

1.62 (0.92-2.85)

   Prior to pregnancy

111

29.6

82

22.3

1.56 (1.11-2.18)

1.66 (1.16-2.37)

History of Physician Diagnosed Migraine

     

   No

350

93.3

348

94.6

1.00 (referent)

1.00 (referent)

   Yes

25

6.7

20

5.4

1.24 (0.68-2.28)

1.13 (0.60-2.12)

  1. 1Adjusted by maternal age, education, smoking status, alcohol consumption, prenatal care utilization and maternal depression status
  2. 2Women with non-migrainous headache disorders were deleted from this analysis; column percentages will not sum to 100%