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Table 3 Results of linear regression analysis (unadjusted and adjusted) for the relationship between patterns of oral contraceptive use and IGF-1 levels (ng/ml) for women aged 18 to 21 years.

From: A cross-sectional study of different patterns of oral contraceptive use among premenopausal women and circulating IGF-1: implications for disease risk

   

Unadjusted

Adjusteda

 

No.

Mean (SD)

Beta

95%CI

P

Beta

95%CI

P

OC Use

        

Never

100

336.8 (111.5)

Reference

0.002

Reference

0.0004

Ever

80

288.7 (87.6)

-48.1

-78.2, -18.0

 

-57.2

-88.7, -25.8

 

Never

100

336.8 (111.5)

Reference

0.007

Reference

0.002

Past

29

295.6 (82.8)

-41.2

-83.6, 1.2

 

-51.7

-94.6, -8.8

 

Current

51

284.7 (90.8)

-52.1

-86.6, -17.5

 

-60.2

-95.5, -24.9

 

Ever Users

        

Age at first use

        

10 to 15 years

11

316.6 (103.4)

43.1

-23.2, 109.3

0.44

34.2

-36.7, 105.0

0.61

16 to 18 years

50

288.3 (87.9)

14.7

-32.4, 61.8

 

17.4

-44.7, 54.1

 

19 to 21 years

19

273.6 (77.2)

Reference

 

Reference

 

Time since last use

        

Current

51

284.7 (90.8)

Reference

0.67

Reference

0.60

< 1 year

11

310.6 (29.3)

25.9

-32.5, 84.3

 

28.7

-30.0, 87.4

 

≥ 1 year

18

286.4 (102.7)

1.7

-46.5, 49.9

 

-1.7

-50.8, 47.5

 

Total duration of use

        

< 1 year

12

273.6 (78.8)

-14.8

-76.3, 46.6

0.80

-11.8

-77.3, 53.7

0.82

1 to 2 years

42

293.2 (86.7)

4.7

-39.2, 48.7

 

7.0

-37.6, 51.6

 

>2 years

26

288.4 (95.1)

Reference

 

Reference

 
  1. a Adjusted for age (18 vs. 19 to 21) and ethnicity (East Asian, South Asian, Other/Mixed vs. European)