Figure 2
From: The role of female hormones on lung function in chronic lung diseases
Used with permission from the American Physiological Society. A) Overview of the sex steroid hormone biosynthetic pathway and associated nuclear receptors. P450ssc, P450-linked side chain cleaving enzyme; CYP17, cytochrome P450 17; 3β-HSD, 3β-hydroxysteroid dehydrogenase; 17β-HSD, 17β-hydroxysteroid dehydrogenase; PR, progesterone receptor; AR, androgen receptor; ER, estrogen receptor. B) Progesterone, C) estriol, D) estradiol, E) estrone [9].