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Table 1 Characteristics of study subjects with SLE (IVCY group and steroid group)

From: Association between low-dose pulsed intravenous cyclophosphamide therapy and amenorrhea in patients with systemic lupus erythematosus: A case-control study

  IVCY group Steroid group p
  n = 29 n = 33  
Age (years) 31 (18-45) 30 (19-45) 0.16
   Subjects < 40 years old 21 (72%) 30 (91%)  
   Subjects ≥ 40 years old 8 (28%) 3 (9%) 0.09
Duration of SLE (months) 7 (1-153) 2 (1-241) 0.05
SLE manifestation    
   Nephritis 15 (52%) 13 (39%) 0.44
   CNS lupus 7 (24%) 1 (3%) 0.02
   Vasculitis 5 (17%) 1 (3%) 0.09
   Cytopenia 7 (24%) 10 (30%) 0.78
SLEDAI-2K 16 (2-31) 10 (3-18) 0.0004
Max. dose of prednisolone (mg) 50 (14-125) 45 (40-100) 0.79
Glucocorticoid pulse therapy 6 (20%) 6 (18%) 1.00
Total dose of cyclophosphamide (mg) 1000 (500-6500)   
Total number of IVCY (time) 2 (1-13)   
  1. *Except where indicated otherwise, values of continuous data are the median (range).
  2. p values were determined by Fisher's exact test or Mann-Whitney U test.
  3. IVCY intravenous cyclophosphamide, SLE systemic lupus erythematosus, CNS central nervous system, SLEDAI-2K systemic lupus erythematosus disease activity index 2000.