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Table 4 Comparisons of menses resumption by age or treatment regimen groups

From: Association between low-dose pulsed intravenous cyclophosphamide therapy and amenorrhea in patients with systemic lupus erythematosus: A case-control study

  Resumed menses Sustained amenorrhea p* OR (95% CI)
  n = 21 n = 5   
Treatment regimen     
   IVCY group 13 (62%) 4 (80%) 0.63 2.5 (0.2-26.1)
   Steroid group 8 (38%) 1 (20%)   -
Age     
   < 40 years old 17 (81%) 0 (0%) 0.002 -
   ≥ 40 years old 4 (19%) 5 (100%)   -
Age < 40 years old     
   IVCY group 11 (52%) 0 (0%) 1.00 -
   Steroid group 6 (29%) 0 (0%)   -
Age ≥ 40 years-old     
   IVCY group 2 (10%) 4 (80%) 0.52 4.0 (0.2-75.7)
   Steroid group 2 (10%) 1 (20%)   -
  1. *p values were determined by Fisher's exact test.
  2. ORs were defined as the ratios of the odds of sustained amenorrhea.
  3. Patients with SLE were divided into 2 groups: those who received low-dose IVCY plus high-dose glucocorticoids (IVCY group) and those who received high-dose glucocorticoids alone (steroid group).
  4. IVCY intravenous cyclophosphamide, SLE systemic lupus erythematosus, OR odds ratio, CI confidence interval.