Table 3 Tumor characteristics of breast cancer molecular subtypes in Egypt
| Â | Total Tissue Cases (N = 203) | Luminal A (N = 90) | Luminal B (N = 50) | HER+/ER- (N = 24) | Unclassified (N = 16) | Basal-like[CK5/6] (N = 23) | p-value |
|---|---|---|---|---|---|---|---|
| Â | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | Â |
Percent of Tissue Cases | 100.0% | 44.3% | 24.6% | 11.8% | 7.9% | 11.3% | Â |
Lymph Nodes | Â | Â | Â | Â | * | * | Â |
   Positive | 74 (70.5%) | 33 (71.7%) | 21 (77.8%) | 11 (78.6%) | 4 (50.0%) | 5 (50.0%) | < 0.0001 |
   Negative | 31 (29.5%) | 13 (28.3%) | 6 (22.2%) | 3 (21.4%) | 4 (50.0%) | 5 (50.0%) |  |
   Not Available | 98 | 44 | 23 | 10 | 8 | 13 |  |
Tumor size, cm (T category) | * | Â | Â | Â | Â | * | Â |
   ≤ 2.0 (T1) | 23 (15.1%) | 11 (15.9%) | 5 (14.7%) | 5 (23.8%) | 2 (15.4%) | 0 (0.0%) | * 0.0002 |
   > 2.0-≤5.0 (T2) | 111 (73.0%) | 51 (73.9%) | 26 (76.5%) | 13 (61.9%) | 8 (61.5%) | 13 (86.7%) |  |
   > 5 (T3) | 18 (11.9%) | 7 (10.1%) | 3 (8.8%) | 3 (14.3%) | 3 (23.1%) | 2 (13.3%) |  |
   Not Available | 51 | 21 | 16 | 3 | 3 | 8 |  |
Histological grade | Â | Â | Â | Â | Â | Â | Â |
   Low Grade (G1) | 1 (0.7%) | 1 (1.5%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.0443 |
   Intermediate Grade (G2) | 120 (82.2%) | 51 (78.5%) | 34 (85.0%) | 13 (86.7%) | 10 (76.9%) | 12 (92.3%) |  |
   High Grade (G3) | 25 (17.1%) | 13 (20.0%) | 6 (15.0%) | 2 (13.3%) | 3 (23.1%) | 1 (7.7%) |  |
   Not available | 57 | 25 | 10 | 9 | 3 | 10 |  |
Histological Type | Â | Â | Â | Â | Â | Â | Â |
   Ductal | 142 (75.5%) | 62 (73.8%) | 41 (87.2%) | 15 (68.2%) | 12 (75.0%) | 12 (63.2%) | < 0.0001 |
   Lobular | 17 (9.0%) | 11 (13.1%) | 3 (6.4%) | 1 (4.5%) | 1 (6.3%) | 1 (5.3%) |  |
   Mixed ductal & lobular | 5 (2.7%) | 3 (3.6%) | 0 (0.0%) | 1 (4.5%) | 1 (6.3%) | 0 (0.0%) |  |
   Medullary | 17 (9.0%) | 3 (3.6%) | 2 (4.3%) | 4 (18.2%) | 2 (12.5%) | 6 (31.6%) |  |
   Other | 7 (3.7%) | 5 (6.0%) | 1 (2.1%) | 1 (4.5%) | 0 (0.0%) | 0 (0.0%) |  |
   Not Available | 15 | 6 | 3 | 2 | 0 | 4 |  |