Figure 6From: Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium Immunohistochemistry reveals that nutlin-3 causes a dose-dependent increase of p53 in fibroids exceeding that in myometrium. A: leiomyoma 695-3, control without nutlin-3; B. myometrium 695-0, control without nutlin-3; C: leiomyoma 695-3 after 6 days exposure to 10 μM nutlin-3; C: myometrium 695-0 after 6 days exposure to 10 μM nutlin-3.Back to article page