Table 2 Associations between alcohol type preference and incident hip fracture in the WHI OS+CT cohort

Alcohol type preference

p=0.0067

p=0.0167

  Prefer beer vs. Non-drinker

0.87 (0.65, 1.18)

1.07 (0.79, 1.46)

  Prefer liquor vs. Non-drinker

1.04 (0.83, 1.31)

0.90 (0.71, 1.14)

  No strong preference vs. Non-drinker

0.76 (0.61, 0.96)

0.87 (0.68, 1.11)

  Infrequent drinker vs. Non-drinker

0.94 (0.76, 1.16)

1.06 (0.85, 1.32)

  Prefer wine vs. Non-drinker

0.76 (0.63, 0.91)

0.78 (0.64, 0.95)

  Past drinker vs. Non-drinker

0.89 (0.73, 1.09)

0.92 (0.75, 1.13)

Ethnicity

p<.0001

  American Indian or Alaska Native vs. White

0.81 (0.30, 2.18)

  Asian or Pacific Islander vs. White

0.32 (0.19, 0.53)

  Black or African-American vs. White

0.32 (0.22, 0.46)

  Hispanic or Latino vs. White

0.31 (0.17, 0.55)

  Other vs. White

0.51 (0.25, 1.02)

Age group at screening

p<.0001

  60-69 vs. 50-59

2.78 (2.25, 3.45)

  70-79 vs. 50-59

9.37 (7.59, 11.56)

Education

p=0.8491

  HS vs. College

1.04 (0.91, 1.19)

  Some college vs. College

1.03 (0.90, 1.19)

Osteoporosis at screening

p<.0001

  No vs. Yes

0.58 (0.49, 0.68)

Falls in the past year

p<.0001

  1 vs. None

1.15 (1.00, 1.32)

  2 vs. None

1.45 (1.20, 1.75)

  3+ vs. None

2.13 (1.69, 2.68)

Previous hip fracture at age 55+

p=0.0005

  No vs. Yes

0.45 (0.28, 0.70)

Parent had hip fracture at age 40+

p<.0001

  No vs. Yes

0.68 (0.59, 0.78)

Bisphosphonate drug at screening

p=0.1166

  No vs. Yes

1.30 (0.94, 1.81)

Smoking status

p=0.0053

  Current vs. Never

1.42 (1.15, 1.77)

  Past vs. Never

1.02 (0.91, 1.16)

Hormone therapy status

p<.0001

  Current vs. Never

0.65 (0.57, 0.74)

  Past vs. Never

0.75 (0.64, 0.87)

Physical activity

p<.0001

  METs per week

0.99 (0.98, 0.99)

BMI Category

p<.0001

  Underweight vs. Normal

1.98 (1.37, 2.85)

  Overweight vs. Normal

0.67 (0.58, 0.76)

  Obese I vs. Normal

0.49 (0.41, 0.58)

  Obese II vs. Normal

0.52 (0.40, 0.68)

  Obese III vs. Normal

0.39 (0.25, 0.59)