Table 4 Comparison of the molecular subtypes among the five Brazilian geographic regions according to age of patients at diagnosis
From: Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil
Geographic regions | Molecular subtypes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Luminal A | Luminal B | Triple-positive | HER2 | Triple-negative | ||||||
Age at diagnosis | <50y | ≥50y | <50y | ≥50y | <50y | ≥50y | <50y | ≥50y | <50y | ≥50y |
Southeast | 188/810 (23.2%) | 519/1651 (31.4%) | 332/810 (41.0%) | 639/1651 (38.7%) | 94 /810 (11.6%) | 144/1651 (8.7%) | 60/810 (7.4%) | 135/1651 (8.2%) | 135/810 (16.7%) | 210/1651 (12.7%) |
South | 91/387 (23.5%) | 233/669 (34.8%) | 150/387 (38.7%) | 238 /669 (35.6%) | 57/387 (14.7%) | 57/669 (8.5%) | 25/387 (6.5%) | 46/669 (6.9%) | 63/387 (16.3%) | 91/669 (13.6%) |
Northeast | 58/348 (16.7%) | 168/592 (28.4%) | 130/348 (37.3%) | 217/592 (36.7%) | 58/348 (16.7%) | 42/592 (7.1%) | 37/348 (10.6%) | 62/592 (10.5%) | 64/348 (18.4%) | 99/592 (16.7%) |
Central West | 43/218 (19.7%) | 100/332 (30.1%) | 80/218 (36.7%) | 110/332 (33.1%) | 37/218 (17.0%) | 34/332 (10.2%) | 19/218 (8.7%) | 30/332 (9.0%) | 39/218 (17.9%) | 56/332 (16.9%) |
North | 36/262 (13.7%) | 135/415 (32.5%) | 90 /262 (34.3%) | 118/415 (28.4%) | 28/262 (10.7%) | 40/415 (9.6%) | 35/262 (13.4%) | 56/415 (13.5%) | 72/262 (27.5%) | 65/415 (15.6%) |