Role of vascular endothelial growth factor polymorphisms (-2578C > A, -460 T > C, -1154G > A, +405G > C and +936C > T) in endometriosis: a case–control study with Brazilians

Table 3 Genotypic distribution of VEGF SNPs in endometriosis patients and controls

SNP	Population	N*	Genotypic distribution N (%)			P χ²
-2578C > A			CC	CA	AA
	Controls	111	50 (45.0)	47 (42.3)	14 (12.7)	0.19
	Cases	178	61 (34.3)	90 (50.6)	27 (15.1)	0.19
-460 T > C			TT	TC	CC
	Controls	107	39 (36.4)	51 (47.7)	17 (15.9)	0.50
	Cases	179	54 (30.2)	97 (54.2)	28 (15.6)	0.50
-1154G > A			GG	GA	AA
	Controls	106	74 (69.8)	30 (28.3)	2 (1.9)	0.01
	Cases	161	90 (55.9)	56 (34.8)	15 (9.3)	0.01
+405G > C			GG	GC	CC
	Controls	110	38 (34.6)	56 (50.9)	16 (14.5)	0.16
	Cases	181	83 (45.9)	75 (41.4)	23 (12.7)	0.16
+936C > T			CC	CT	TT
	Controls	95	67 (70.5)	27 (28.4)	1 (1.1)	0.63
	Cases	165	120 (72.8)	41 (24.8)	4 (2.4)	0.63

N* is the number of examined samples of cases and controls for each SNP. Differences in sample sizes are due to available data from PCR amplification for each SNP. P χ2 is P from Chi-square test (Pearson p-value) or Fisher’s exact test.

ISSN: 1472-6874