Skip to main content

Advertisement

Table 3 Genotypic distribution of VEGF SNPs in endometriosis patients and controls

From: Role of vascular endothelial growth factor polymorphisms (-2578C > A, -460 T > C, -1154G > A, +405G > C and +936C > T) in endometriosis: a case–control study with Brazilians

SNP Population N* Genotypic distribution N (%) P χ2
-2578C > A    CC CA AA  
  Controls 111 50 (45.0) 47 (42.3) 14 (12.7) 0.19
  Cases 178 61 (34.3) 90 (50.6) 27 (15.1)
-460 T > C    TT TC CC  
  Controls 107 39 (36.4) 51 (47.7) 17 (15.9) 0.50
  Cases 179 54 (30.2) 97 (54.2) 28 (15.6)
-1154G > A    GG GA AA  
  Controls 106 74 (69.8) 30 (28.3) 2 (1.9) 0.01
  Cases 161 90 (55.9) 56 (34.8) 15 (9.3)
+405G > C    GG GC CC  
  Controls 110 38 (34.6) 56 (50.9) 16 (14.5) 0.16
  Cases 181 83 (45.9) 75 (41.4) 23 (12.7)
+936C > T    CC CT TT  
  Controls 95 67 (70.5) 27 (28.4) 1 (1.1) 0.63
  Cases 165 120 (72.8) 41 (24.8) 4 (2.4)
  1. N* is the number of examined samples of cases and controls for each SNP. Differences in sample sizes are due to available data from PCR amplification for each SNP. P χ2 is P from Chi-square test (Pearson p-value) or Fisher’s exact test.