Independent external validation of cardiovascular disease mortality in women utilising Framingham and SCORE risk models: a mortality follow-up study

Table 1 Characteristics of the cohort of 4487 women without heart disease, diabetes or stroke at baseline

Variables	Total cohort	Survivors	Deaths (all-cause)	CVD deaths
Variables	n = 4487	n = 4335	n = 152	n = 28
Age (years)	42.8 ± 13.2	42.3 ± 13.0	56.0 ± 11.9	60.8 ± 8.1
BMI (kg/m²)	24.8 ± 4.7	24.8 ± 4.7	26.2 ± 5.0	26.5 ± 3.8
WC (cm)	76.2 ± 11.1	76.0 ± 11.0	81.2 ± 10.7	82.5 ± 10.3
WHR	0.76 ± 0.06	0.76 ± 0.06	0.79 ± 0.07	0.80 ± 0.06
SBP (mmHg)	122.1 ± 18.4	121.6 ± 18.0	134.2 ± 23.4	143.7 ± 29.4
TC (mmol/L)	5.5 ± 1.2	5.4 ± 1.1	6.0 ± 1.2	6.5 ± 1.2
HDL-C (mmol/L)	1.5 ± 0.4	1.5 ± 0.4	1.5 ± 0.4	1.5 ± 0.4
Ratio of TC to HDL-C	3.9 ± 1.3	3.9 ± 1.3	4.3 ± 1.5	4.9 ± 2.2
Non-smoker	2652 (59.1%)	2570 (59.3%)	82 (54.0%)	13 (46.4%)
Previous smoker	880 (19.6%)	854 (19.7%)	26 (17.1%)	4 (14.3%)
Current smoker	955 (21.3%)	911 (21.0%)	44 (28.9%)	11 (39.3%)
FPR (%)	0.8 ± 1.8	0.7 ± 1.7	2.9 ± 3.7	5.2 ± 5.8
SCORE-Low (%)	0.7 ± 1.9	0.7 ± 1.6	3.1 ± 5.2	6.1 ± 9.9
SCORE-High (%)	1.1 ± 2.8	1.0 ± 2.4	4.5 ± 7.3	8.9 ± 13.8
FPR (%)	0.1 (0 , 0.6)	0.1 (0 , 0.5)	1.5 (0.2 , 4.1)	3.1 (1.0 , 6.6)
SCORE-Low (%)	0.1 (0 , 0.6)	0.1 (0 , 0.5)	1.8 (0.2 , 3.7)	2.9 (1.0 , 5.7)
SCORE-High (%)	0.1 (0 , 0.9)	0.1 (0 , 0.8)	2.8 (0.4 , 5.6)	4.3 (1.5 , 8.6)

Abbreviations: BMI, body mass index; WC, waist circumference; WHR, waist to hip ratio; SBP, systolic blood pressure; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; FPR, Framingham 10-year predicted risk for CVD death; SCORE-Low, SCORE-Low 10-year predicted risk for CVD death; SCORE-High, SCORE-High 10-year predicted risk for CVD death.

ISSN: 1472-6874