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Table 3 Carotid plaques in the common carotid artery and reproductive parameters in 800 postmenopausal women, the KORA F4 study

From: Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study of postmenopausal women enrolled in the population-based KORA F4 study

 

Age-adjusted

  

Multivariable-adjusted

  
 

OR

95% CI

p-value

OR

95% CI

p-value

Menarche

      

<12 years

2.23

1.13-4.43

0.018

2.11

1.05-4.26

0.037

12-15 years**

      

>15 years

1.22

0.77-1.92

0.290

1.25

0.79-1.99

0.436

Parity

      

0

1.37

0.83-2.26

0.195

1.41

0.83-2.38

0.186

1-2

1.01

0.73-1.41

0.397

1.02

0.73-1.42

0.383

>2**

      

Age at menopause 1

      

≥ 50 years

0.94

0.66-1.33

0.714

1.00

0.70-1.45

0.962

< 50 years**

      

Time since menopause 1

      

> 15 years

0.97

0.58-1.63

0.921

0.91

0.54-1.53

0.772

≤ 15 years**

      

Duration of fertility 1

      

> 35.0 years

0.84

0.59-1.20

0.339

0.87

0.61-1.25

0.449

≤ 35.0 years**

      

Current use of HRT

      

Yes

0.78

0.49-1.24

0.294

0.79

0.49-1.26

0.316

No**

      

Ever use of HRT

      

Yes

0.60

0.44-0.81

0.001

0.62

0.45-0.86

0.003

No**

      

Ever use of OC

      

Yes

1.25

0.89-1.78

0.203

1.34

0.93-1.90

0.125

No**

      

Hysterectomy

      

Yes

0.84

0.61-1.16

0.285

0.83

0.60-1.16

0.284

No**

      

Bilateral oophorectomy

      

Yes

0.68

0.37-1.26

0.221

0.65

0.35-1.22

0.178

No**

      

Hot flashes

      

Yes

0.93

0.67-1.30

0.664

0.90

0.64-1.26

0.535

No**

      

Depressed mood

      

Yes

1.16

0.84-1.60

0.367

1.15

0.83-1.59

0.396

No**

      
  1. Logistic regression analyses.
  2. Abbreviations: HRT: Hormone replacement therapy, OC: oral contraceptives
  3. **reference group.
  4. Multivariable-adjusted: Age, BMI, education, family status, physical activity, smoking, alcohol consumption, total cholesterol, triglycerides and fasting blood glucose.
  5. 1n = 602, due to missing values of age at menopause.