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Table 1 Cases of solitary fibrous tumours of the uterine cervix reported in the literature

From: A case of a large solitary fibrous tumour of the uterine cervix

Author Patient’s age (years) Maximal diameter of tumour (cm) Immunohistochemical profile Symptoms Treatment Follow-up Outcome
Hasegawa et al. [3, 5] 78 6 (+): MIB1-LI 0.5%, bcl-2, CD34 (-): S100, CK, desmin, CD31, α-SMA, EMA Abnormal vaginal bleeding Excision (not specified) 11 years NR
Sidebotham et al. [4] 14 1.7 (+): MIB1-LI 5%, CD34, patchy (+): S100, CD68, focally (+): ER, PR, SMA, (-): bcl-2, desmin, myogenin, WT-1, CD99, CD1a, HMB-45, alk Abnormal vaginal bleeding Abdominal radical trachelectomy 2 weeks Alive, NR
Rahimi et al. [2] 68 1.7 (+): vim, CD99, CD34, bcl-2, ER, PR, β-catenin, (-): EMA, S100, factor XIIIa, CKAE1/AE3, caldesmon, desmin, CD31, SMA None Robotic assisted radical hysterectomy* NA NA
Current case 45 16 (+): CD34, bcl-2, vim, focally (+): SMA, desmin, (-): S100, CKAE1/AE3 Abnormal vaginal bleeding, low abdominal pain Radical hysterectomy 8 months Alive, NR
  1. (+) – positive immunostaining, MIB1-LI – MIB1 labeling index, bcl-2 – B-cell lymphoma 2, (-) – negative immunostaining, S100 – S100 protein, CK – cytokeratin, α-SMA – α-smooth muscle actin, EMA - epithelial membrane antigen, NR – no recurrence, ER- estrogen receptor, PR – progesterone receptor, SMA – smooth muscle actin, WT-1 – Wilm’s tumour gene, CD1a – CD1a molecule, HMB-45 – human melanoma black monoclonal antibody, alk – anaplastic lymphoma kinase, vim – vimentin, NA – data not available, CKAE1/AE3 – cytokeratin AE1/AE3, *the solitary fibrous tumour accompanied an invasive cervical cancer. All reported cases had benign histology.