From: Obstetric prognosis in sisters of preeclamptic women – implications for genetic linkage studies
reference group | unaffected sisters of preeclamptic index patients | affected sisters of preeclamptic index patients | |
---|---|---|---|
outcome | N = 530 | N = 63 | N = 42 |
Admission to a neonatal intensive care unit | 34 (6.42 %) | 3 (4.76 %) P = 0.786a | 9 (21.43 %) P = 0.002a |
Intrauterine fetal death | 3 (0.57 %) | 0 P = 1.00a | 0 P = 1.00a |
Prematurity (delivery before 37 weeks) | 25 (4.72 %) | 1 (1.59 %) P = 0.344a | 10 (23.80 %) P < 0.001 |
Low birth weight (<2500 g) | 16 (3.02 %) | 0 P = 0.398a | 12 (28.57 %) P < 0.001 |
Small for gestational age (< 10th percentile) | 61 (11.51 %) | 8 (12.70 %) P = 0.781 | 9 (21.43 %) P = 0.059 |
Low Apgar score (<7 at 1 min) | 31 (5.85 %) | 4 (6.35 %) P = 0.780a | 5 (11.90 %) P = 0.173a |
Low Apgar score (<7 at 5 min) | 7 (1.32 %) | 0 P = 1.00a | 0 P = 1.00a |
Fetal venous pH <7.15 at birth | 11 (2.1 %) | 3 (4.76 %) P = 0.175a | 2 (4.76 %) P = 0.250a |