Risk Factors | HER-2/neu+ Cases/controls OR (95% CI) | HER-2/neu-Cases/controls OR (95% CI) | Ratio of the OR's Cases+/cases- OR (95% CI) |
---|---|---|---|
PREMENOPAUSAL | |||
Age at first full pregnancy(≥ 23 years) | NS | 3.56(1.70–7.46) | NS |
Body mass index(>29 kg/m2) | NS | 6.89(2.23–21.25) | NS |
Abortion or miscarriage(ever) | NS | 0.49(0.23–1.05) | 3.12 (1.18–8.24) |
First degree family history(positive) | NS | 3.30(1.10–9.96) | 0.09 (0.01–0.85) |
Use of oral contraceptives (ever) | NS | 11.19(3.7–33.84) | 0.16 (0.04–0.60) |
Age of menarche (≤ 12 years) | 2.09 (0.99–4.42) | NS | NS |
POSTMENOPAUSAL | |||
Age at first full pregnancy(≥ 23 years) | 2.19(1.23–3.91) | 1.66(1.03–2.66) | NS |
Body mass index(>29 kg/m2) | 4.83(2.75–8.49) | 2.67(1.56–4.55) | 2.23 (1.20–4.15) |
Abortion or miscarriage(ever) | 0.50(0.28–0.88) | 0.62(0.39–0.97) | NS |
First degree family history(positive) | NS | 2.23(1.08–4.63) | NS |
Use of estrogens (ever) | NS | 10.70(2.71–42.31) | 0.21 (0.04–1.08) |
Use of oral contraceptives (ever) | NS | 6.47(1.89–22.16) | NS |
Age of menarche (≤ 12 years) | NS | 1.72(1.07–2.75) | 0.54 (0.28–1.04) |
ALL WOMEN | |||
Age at first full pregnancy(≥ 23 years) | 2.19(1.23–3.91) | 1.66 (1.03–2.66) | NS |
Body mass index(>29 kg/m2) | 4.83(2.75–8.49) | 2.67(1.56–4.55) | 2.23(1.20–4.15) |
Abortion or miscarriage(ever) | 0.50(0.28–0.88) | 0.62(0.39–0.97) | NS |
First degree family history(positive) | NS | 2.23(1.08–4.63) | NS |
Use of estrogens (ever) | NS | 10.70(2.71–42.31) | 0.21 (0.04–1.08) |
Use of oral contraceptives (ever) | NS | 6.47(1.88–22.16) | NS |
Age of menarche (≤ 12 years) | NS | 1.72(1.07–2.75) | 0.54 (0.28–1.04) |