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Table 1 Histology results

From: Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

 

Patients with no breast pain (N = 8)

Patients with breast pain (N = 10)

P-Mann Whitney Test

Intra-epidermal

Median (range)

Median (range)

 

TRPV1 intra-epidermal fibres

0.69 (0.00 – 1.27)

2.15 (0.77 – 4.38)

0.0009**

TRPVR1 fibre "clusters"

0.15 (0.00 – 0.27)

0.37 (0.00–0.85)

0.0085*

Sub-epidermal

   

TRPV1 fibres

2.98 (1.59–4.04)

3.79 (0.63 – 5.92)

0.1457

Neurofilament fibres

3.38 (0.83 – 5.92)

2.95 (0.94 – 4.95)

0.7618

NGF staining

2.5 (1.0–3.0)

2.38 (1.0–3.0)

0.5726

Epidermal Thickness (mm)

0.04 (0.02 – 0.12)

0.04 (0.03 – 0.05)

0.9654