Table 2 Determinants of HRT discontinuation: results of propensity analysis
| Â | Â | Â | Multivariate Logistic Regression Results* | ||||
|---|---|---|---|---|---|---|---|
Variable | HRT Continuers (N = 1342) | HRT Discontinuers (N = 1015) | Parameter Estimate (β) | Std. Error of β | Adjusted Odds Ratio | 95% CI for Odds Ratio | P-value |
Age | Â | Â | Â | Â | Â | Â | Â |
   Age in years (mean) | 75.5 | 75.5 | 0.0081 | 0.0075 | 1.041 | 0.993–1.023 | .2847 |
Race | Â | Â | Â | Â | Â | Â | Â |
   White (%) †| 96.7 | 95.6 | -- | -- | 1.000 | -- | -- |
   Black (%) | 2.7 | 3.5 | 0.3536 | 0.2527 | 1.424 | 0.868–2.337 | .1616 |
   Other race (%) | 0.6 | 1.0 | 0.2903 | 0.4992 | 1.337 | 0.503–3.556 | .5609 |
Income | Â | Â | Â | Â | Â | Â | Â |
   Annual income in thousands (mean) | $13.805 | $13.999 | 0.0537 | 0.0245 | 1.055 | 1.006–1.117 | .0283 |
Marital status | Â | Â | Â | Â | Â | Â | Â |
   Widowed, divorced, or never married (%) †| 80.6 | 80.5 | -- | -- | 1.000 | -- | -- |
   Currently married (%) | 19.4 | 19.5 | -0.1327 | 0.1384 | 0.876 | 0.668–1.149 | .3378 |
Education | Â | Â | Â | Â | Â | Â | Â |
   12 or more years of education (%) | 60.5 | 63.5 | 0.0937 | 0.0899 | 1.098 | 0.921–1.310 | .2971 |
Residence type | Â | Â | Â | Â | Â | Â | Â |
   Nursing or personal care facility (%) | 1.6 | 1.0 | -0.4390 | 0.4067 | 0.645 | 0.291–1.431 | .2804 |
Urban/rural residence | Â | Â | Â | Â | Â | Â | Â |
   Semi-rural or rural residence (%) | 33.6 | 35.5 | 0.1526 | 0.0913 | 1.165 | 0.974–1.393 | .0948 |
Alcohol use | Â | Â | Â | Â | Â | Â | Â |
   Current alcohol user (%) | 26.5 | 24.4 | -0.1335 | 0.1008 | 0.875 | 0.995–1.022 | .1854 |
Smoking history | Â | Â | Â | Â | Â | Â | Â |
   Past or present smoker (%) | 34.7 | 33.0 | -0.0573 | 0.0924 | 0.944 | 0.788–1.132 | .5352 |
Type of HRT used at baseline | Â | Â | Â | Â | Â | Â | Â |
   Unopposed estrogen (%) †| 89.5 | 74.2 | -- | -- | 1.000 | -- | -- |
   Combination estrogen/progestin (%) | 10.5 | 25.8 | 1.1100 | .1171 | 3.034 | 2.412–3.817 | .0001 |
Baseline non-HRT prescription drug use | Â | Â | Â | Â | Â | Â | Â |
   Any cardiovascular drug use (%) | 78.8 | 79.9 | 0.2265 | 0.1141 | 1.254 | 1.003–1.568 | .0471 |
   Any osteoporosis treatment (%) | 12.2 | 15.4 | 0.3100 | 0.1270 | 1.363 | 1.063–1.749 | .0146 |
   Total number of non-HRT drug classes (mean) | 6.3 | 5.9 | -0.0507 | 0.0165 | 0.951 | 0.920–0.982 | .0021 |
Baseline HRQOL | Â | Â | Â | Â | Â | Â | Â |
   Days that physical health was not good (mean) | 6.3 | 6.3 | 0.0086 | 0.0069 | 1.009 | 0.995–1.022 | .2174 |
   Days that mental health was not good (mean) | 3.3 | 3.0 | -0.0042 | 0.0067 | 0.996 | 0.983–1.009 | .5323 |
   Healthy days (mean) ‡ | 21.9 | 22.3 | -- | -- | -- | -- | -- |
   Days that health interfered (mean) | 4.2 | 3.8 | -0.0113 | 0.0077 | 0.989 | 0.974–1.004 | .1432 |
   Days that pain made it hard (mean) | 6.3 | 6.4 | 0.0060 | 0.0064 | 1.006 | 0.993–1.019 | .3514 |