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Figure 1 | BMC Women's Health

Figure 1

From: Aberrations of TACC1 and TACC3 are associated with ovarian cancer

Figure 1

Immunohistochemical analysis of tumor micoarrays. Representative normal human ovarian surface epithelium and tumor cores stained for TACC1 (panels A-E), and TACC3 (panels F-J) proteins to show positive and negative staining. TACC protein expression is detected as a brown signal against the blue Hematoxylin counterstain. In all cases where TACC3 expression was observed, the protein was excluded from the nucleus of the ovarian tumor cells, unlike the observable nuclear and cytoplasmic expression of TACC1. A, normal ovarian surface epithelium with nuclear/cytoplasmic TACC1 staining; B, serous papillary TACC1 +ve; C, serous papillary TACC1 -ve; D, endometroid TACC1 +ve; E, endometroid TACC1 -ve; F, normal ovarian surface epithelium with nuclear TACC3 staining; G, serous papillary TACC3 +ve; H, serous papillary TACC3 -ve; I, clear cell TACC3 +ve; J, clear cell TACC3 -ve. A-H: Main panel original magnification ×40; insets show whole tumor core at original magnification ×10.

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