Figure 2

Imaging of subject 006. A) Subject 006 pre-MRI mammogram demonstrating heterogeneously dense breast tissue. There is no evidence of a cancerous lesion. B) Pre-contrast MR image showing an approximately 1.5 cm, smooth, round lesion in the right breast just above the nipple level medial and close to the chest wall (arrowhead). Core biopsy of this lesion demonstrated benign pathology, specifically, fibrosis with focal ductal epithelial hyperplasia [44]. C) Post-contrast MR images showing a small (approximately 1 cm), round, well-delineated enhancing mass (arrow) in the left breast at the 1:00 position. This mass was seen on both the initial delay after contrast injection (left) and the delayed contrast enhanced subtraction images (right). Core biopsy of this lesion indicated infiltrating ductal carcinoma, which was confirmed after removal via modified radical mastectomy [44].