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Table 3 Unadjusted, adjusted, and multivariate analyses of factors influencing the ability to obtain nipple aspirate fluid (NAF), Sartorius Nipple Aspirate Fluid Cohort, 1970–1990.

From: A descriptive study of variables associated with obtaining nipple aspirate fluid in a cohort of non-lactating women

 

No NAF Obtained

NAF Obtained

Chi-square

Age-adjusted Odds

Multivariate* adjusted Odds

VARIABLE

N (%)

N (%)

p-value

Ratio

95% CI*

p-value

Ratio

95% CI

p-value

Marital Status

           

No

617 (60.8)

398 (39.2)

         

Yes

988 (53.9)

845 (46.1)

0.0004

1.39

1.19

1.63

<0.0001

1.30

1.06

1.59

0.01

Age at Menarche

           

13 and older

981 (62.3)

595 (37.8)

0.004

1.19

1.01

1.41

0.04

1.18

0.98

1.43

0.08

12 or younger

548 (56.5)

422 (43.5)

         

Pregnancy History

           

Never pregnant

546 (61.6)

341 (38.4)

         

Ever pregnant

1183 (54.9)

972 (45.1)

0.0007

1.66

1.40

1.97

<0.0001

1.55

1.24

1.94

0.0001

Breastfed Children

           

Never Breastfed

483 (55.5)

387 (44.5)

         

Ever Breastfed

663 (54.8)

546 (45.2)

0.76

0.96

0.80

1.15

0.65

    

Menopause

           

No

845 (52.8)

755 (47.2)

         

Yes

838 (63.1)

490 (36.9)

<0.0001

1.04

0.84

1.29

0.73

    

Estrogen Use

           

No

1116 (56.1)

755 (47.2)

         

Yes

580 (63.2)

489 (36.9)

0.02

1.23

1.02

1.48

0.03

    

Menopausal status and Estrogen use

           

Premenopausal women

822 (53.3)

721 (46.7

<0.0001

referent

   

referent

   

Menopausal and NO estrogen

293 (62.9)

173 (37.1)

 

1.00

0.77

1.29

0.99

0.76

0.55

1.04

0.09

Menopausal and estrogen

538 (64.2)

300 (35.8)

 

1.01

0.79

1.28

0.94

0.71

0.52

0.95

0.02

Oral Contraceptive Pills

           

No

715 (63.6)

409 (36.4)

         

Yes

873 (55.3)

707 (44.8)

<0.0001

0.98

0.82

1.17

0.82

    

Tranquilizer Use

           

No

1501 (59.8)

1009 (40.2)

         

Yes

145 (39.7)

220 (60.3)

<0.0001

2.50

2.00

3.15

<0.0001

2.20

1.63

2.98

<0.0001

Endocrine Problems

           

Never

1401 (58.6)

992 (41.5)

         

Ever had

273 (53.7)

235 (46.3)

0.05

1.47

1.21

1.80

0.0001

1.39

1.07

1.81

0.01

  1. * Multivariate model is adjusted for age, marital status, age at menarche, any pregnancy history, the combination of menopausal status and estrogen use, tranquilizer use, and endocrine problems (in the multivariate model N = 2104)
  2. ** CI, Confidence interval
  3. Total number of women for whom NAF fluid was not obtained = 1729 (56.8%)
  4. Total number of women for whom NAF fluid was obtained = 1314 (43.2%)
  5. Total number of women, N = 3043