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Table 3 Comparison of the biological activities of progesterone and drospirenone with other progestogens (28)

From: Advances in hormone replacement therapy: making the menopause manageable

Progestogens

Biological activities

 

Progestogenic

Androgenic

Anti-androgenic

Anti-aldosterone

Glucocorticoid

Progesterone

+

-

±

+

-

Drospirenone

+

-

+

+

-

Cyproterone acetate

+

-

+

-

±

Dienogest

+

-

+

-

-

Levonorgestrel

+

±

-

-

-

Medroxyprogesterone acetate

+

±

-

-

±

Norethisterone

+

±

-

-

-

Trimegestone

+

-

±

±

-

Norgestimate

+

±

-

-

-

  1. Clinically relevant activity (+); activity not clinically relevant (±); no activity (-)