From: Breast cancer risk and genetic ancestry: a case–control study in Uruguay
Cases | Controls | p-value | |
---|---|---|---|
Age at diagnosis/recruitment (years) | |||
mean ± SD | 56.6 ± 10.1 | 52.8 ± 8.9 | <0.001 |
Place of residence (%) | |||
Montevideo | 86.5 | 87.2 | 0.85 |
Outside Montevideo | 13.5 | 12.8 | |
Location (%) | |||
Urbana | 85.5 | 90.6 | 0.17 |
Rural | 14.5 | 9.4 | |
Hospital (%) | |||
Public | 87.2 | 84.8 | 0.54 |
Private | 12.8 | 15.2 | |
Age at menarche (years) f | |||
mean ± SD | 12.3 ± 1.5 | 12.2 ± 1.4 | 0.56 |
Oral contraceptives (%) | |||
Yes | 66.2 | 73.8 | 0.15 |
No | 33.8 | 26.2 | |
Children (%) t | |||
Yes | 90.5 | 91.5 | 0.78 |
No | 9.5 | 8.5 | |
Age at first child (years) j | |||
mean ± SD | 25.6 ± 6.0 | 23.4 ± 6.0 | 0.01 |
Number of children (%) i | |||
mean ± SD | 2.46 ± 1.52 | 2.52 ± 1.73 | 0.75 |
Breastfeeding (%) k | |||
Yes | 80.2 | 85.5 | 0.24 |
No | 19.8 | 14.5 | |
Menopause g,r (%) | |||
Yes | 65.2 | 52.1 | 0.03 |
No | 34.9 | 47.9 | |
Age at menopause (years) h,s | |||
mean ± SD | 49.2 ± 5.0 | 47.6 ± 4.3 | 0.07 |
Breast cancer in the family (%) | |||
Yes | 18.2 | 9.8 | 0.03 |
No | 81.8 | 90.2 | |
Smoking (%) l | |||
Yes | 47.3 | 53.4 | 0.28 |
No | 52.7 | 46.6 | |
Passive smoker before 20 years old (%) m | |||
Yes | 55.4 | 54.0 | 0.81 |
No | 44.6 | 46.0 | |
Red meat intake c (%) n,u | |||
Yes | 95.1 | 100.0 | 0.01v |
No | 4.9 | 0.0 | |
Education (%) | |||
Primary school | 37.8 | 32.3 | 0.001 |
Secondary school | 53.3 | 43.3 | |
University | 8.9 | 24.4 | |
Occupation (%) o | |||
Unemployed/never worked | 9.6 | 0.6 | <0.001v |
Self-employed | 84.3 | 70.0 | |
Public/private employee | 3.4 | 10.0 | |
Teacher | 2.7 | 4.4 | |
Retired | 0.0 | 4.4 | |
Professional | 0.0 | 10.6 | |
Income (U$S per month, %) p | |||
<175 | 6.1 | 7.0 | <0.001 |
175-750 | 87.0 | 66.7 | |
>750 | 6.9 | 26.3 | |
Source of income (%) q | |||
Social security/family | 12.2 | 3.7 | <0.001v |
Pension | 20.9 | 4.4 | |
Salary | 64.2 | 88.8 | |
Rent | 2.7 | 1.2 | |
Other | 0.0 | 1.9 | |
Socioeconomic status (%) | |||
Low | 38.5 | 32.3 | 0.25 |
Medium | 61.5 | 67.7 | |
Weight (kg) b | |||
mean ± SD | 71.2 ± 14.9 | 68.5 ± 13.5 | 0.11 |
Height (m) c | |||
mean ± SD | 1.60 ± 0.07 | 1.59 ± 0.07 | 0.31 |
BMI (kg/m 2 ) d | |||
mean ± SD | 27.7 ± 5.3 | 27.0 ± 5.1 | 0.22 |
Waist-hip ratio e | |||
mean ± SD | 0.87 ± 0.07 | 0.86 ± 0.08 | 0.17 |
Ancestry (%) mean ± SD | |||
African | 9.8 ± 7.6 | 9.1 ± 7.5 | 0.33 |
Native American | 13.2 ± 10.2 | 14.7 ± 11.2 | 0.26 |
European | 77.1 ± 13.1 | 76.2 ± 14.2 | 0.73 |