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Table 1 Characteristics of the study population

From: Breast cancer risk and genetic ancestry: a case–control study in Uruguay

 

Cases

Controls

p-value

Age at diagnosis/recruitment (years)

   

mean ± SD

56.6 ± 10.1

52.8 ± 8.9

<0.001

Place of residence (%)

   

Montevideo

86.5

87.2

0.85

Outside Montevideo

13.5

12.8

 

Location (%)

   

Urbana

85.5

90.6

0.17

Rural

14.5

9.4

 

Hospital (%)

   

Public

87.2

84.8

0.54

Private

12.8

15.2

 

Age at menarche (years) f

   

mean ± SD

12.3 ± 1.5

12.2 ± 1.4

0.56

Oral contraceptives (%)

   

Yes

66.2

73.8

0.15

No

33.8

26.2

 

Children (%) t

   

Yes

90.5

91.5

0.78

No

9.5

8.5

 

Age at first child (years) j

   

mean ± SD

25.6 ± 6.0

23.4 ± 6.0

0.01

Number of children (%) i

   

mean ± SD

2.46 ± 1.52

2.52 ± 1.73

0.75

Breastfeeding (%) k

   

Yes

80.2

85.5

0.24

No

19.8

14.5

 

Menopause g,r (%)

   

Yes

65.2

52.1

0.03

No

34.9

47.9

 

Age at menopause (years) h,s

   

mean ± SD

49.2 ± 5.0

47.6 ± 4.3

0.07

Breast cancer in the family (%)

   

Yes

18.2

9.8

0.03

No

81.8

90.2

 

Smoking (%) l

   

Yes

47.3

53.4

0.28

No

52.7

46.6

 

Passive smoker before 20 years old (%) m

   

Yes

55.4

54.0

0.81

No

44.6

46.0

 

Red meat intake c (%) n,u

   

Yes

95.1

100.0

0.01v

No

4.9

0.0

 

Education (%)

   

Primary school

37.8

32.3

0.001

Secondary school

53.3

43.3

 

University

8.9

24.4

 

Occupation (%) o

   

Unemployed/never worked

9.6

0.6

<0.001v

Self-employed

84.3

70.0

 

Public/private employee

3.4

10.0

 

Teacher

2.7

4.4

 

Retired

0.0

4.4

 

Professional

0.0

10.6

 

Income (U$S per month, %) p

   

<175

6.1

7.0

<0.001

175-750

87.0

66.7

 

>750

6.9

26.3

 

Source of income (%) q

   

Social security/family

12.2

3.7

<0.001v

Pension

20.9

4.4

 

Salary

64.2

88.8

 

Rent

2.7

1.2

 

Other

0.0

1.9

 

Socioeconomic status (%)

   

Low

38.5

32.3

0.25

Medium

61.5

67.7

 

Weight (kg) b

   

mean ± SD

71.2 ± 14.9

68.5 ± 13.5

0.11

Height (m) c

   

mean ± SD

1.60 ± 0.07

1.59 ± 0.07

0.31

BMI (kg/m 2 ) d

   

mean ± SD

27.7 ± 5.3

27.0 ± 5.1

0.22

Waist-hip ratio e

   

mean ± SD

0.87 ± 0.07

0.86 ± 0.08

0.17

Ancestry (%) mean ± SD

   

African

9.8 ± 7.6

9.1 ± 7.5

0.33

Native American

13.2 ± 10.2

14.7 ± 11.2

0.26

European

77.1 ± 13.1

76.2 ± 14.2

0.73

  1. N cases = 148; N controls = 164.
  2. Missing data (N cases/N controls): a,b3/4, c10/3, d10/4, e16/29, f0/3, g16/22, h82/115, i,m27/12, j39/25, k27/28, l2/3, n6/12, o2/4, p2/8, q0/3.
  3. rWomen who underwent menopause due to treatment or surgical intervention were excluded. Not all participants who answered this question also responded the question on age at menopause, thus the difference in sample sizes.
  4. sAge at menopause was calculated for women who were ≥ 55 years old and had undergone menopause naturally.
  5. tNot all participants who answered this question also responded the question on age at first child, thus the difference in sample sizes.
  6. uAmong cases, red meat intake corresponds to frequency of intake before being diagnosed with breast cancer.
  7. vFisher’s exact test.