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Table 3 Sensitivity, specificity, accuracy, positive and negative predictive values for fluorescence spectroscopy, colposcopy and combination of methods, analyzing cervical quadrant diagnosis

From: 5-Aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy

 

Fluorescence spectroscopy

Colposcopy

Colposcopy + fluorescence (combined)

n

%

95% CI

n

%

95% CI

n

%

95% CI

Sensitivity

66/92

71.7

61.4- 80.6

62/92

67.4

56.8- 76.8

81/92

88.0

79.6- 93.9

Specificity

62/82

75.6

64.9- 84.4

71/82

86.6

77.3- 93.1

57/82

69.5

58.4- 79.2

Accuracy

128/ 174

73.5

-

133/174

76.4

-

138/174

79.3

-

PPV

66/86

76.7

-

62/73

84.9

-

81/106

76.4

-

NPV

62/88

70.5

-

71/101

70.3

-

57/68

83.8

-

Total

174

 

174

 

174