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Table 5 Sensitivity, specificity, accuracy, positive and negative predictive values for fluorescence spectroscopy, colposcopy and combination of methods, analyzing per patient diagnosis

From: 5-Aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy

 

Fluorescence spectroscopy

Colposcopy

Colposcopy + fluorescence (combined)

n

%

95% CI

n

%

95% CI

n

%

95% CI

Sensitivity

31/34

91.2

76.3- 98.0

30/34

88.2

72.5-96.6

33/ 34

97.1

84.6- 99.5

Specificity

10/14

71.4

41.9- 91.4

11/14

78.6

49.2-95.1

8/14

57.1

28.9- 82.2

Accuracy

41/48

85.4

-

41/48

85.4

-

41/ 48

85.4

-

PPV

31/35

88.6

-

30/33

90.9

-

33/ 39

84.6

-

NPV

10/13

76.9

-

11/15

73.3

-

8/9

88.9

-

Total

48

 

48

 

48