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Table 3 Significant associations for the single SNPs of TNFSF11, TNFRSF11A and TNFRSF11B genes with AAM and AANM

From: Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women

Genotype

n

AAM

Genotype

n

AAM

rs4500848

rs1805034

C/C

471

15.16 ± 1.95

C/C

64

14.53 ± 2.17

C/T

313

14.76 ± 2.07

C/T

358

14.86 ± 2.04

T/T

61

14.57 ± 1.85

T/T

423

15.12 ± 1.93

P-value

 

<0.01

P-value

 

0.04

Genotype

n

AAM

Genotype

n

AANM

rs6567270

rs9962159

A/A

152

15.35 ± 2.07

G/G

166

48.45 ± 4.18

A/T

385

14.92 ± 2.02

G/A

403

48.56 ± 4.23

T/T

308

14.84 ± 1.91

A/A

276

49.26 ± 4.00

P-value

 

0.03

P-value

 

0.05