Table 1 Diagnosis details
From: Management of musculoskeletal tumors during pregnancy: a retrospective study
First symptom | Pregnancy number | Site and size | Histology | Grading and staging | Progression in pregnancy | Pregnancy Outcome: delivery; birth weight; gestational age; sex of fetus; APGAR Score | Treatment | Treatment timing | |
|---|---|---|---|---|---|---|---|---|---|
I | Pain noticed in the period between the25th to the 30th week of pregnancya, later tumescence | 4th in 2009 | Knee joint (right); 16,5x9x12 | Synovial sarcoma | G3; pT2b, pNX, pMX ∆ | Increasing pain and tumescence in the last few weeks of pregnancy, afterwards stable symptoms | Cesarean (due to the patients wish); 2750 g; 36th week; male; 9 | Marginal tumor resection | 8 months postpartum |
II | Pain which occurred in the 37th week of pregnancy | 2nd in 2009 | Fibula dist. (left); maximum of 9 cm | Ewing’s sarcoma | G3; ypT2 ◊ | Walking problems which occurred in the 39th week | Vaginal delivery; 3140 g; 40th week; male; 10 | En-bloc resection | 11 months postpartum |
III | Painful swelling noticed in the 31th week of pregnancy | 2nd in 2010 | Knee joint (left); 13x10x5,5 | Clear cell sarcoma, soft tissue | b; pT2b, pN1(2,6), pM1 (OSS) ◊ | Increasing pain until treatment | Cesarean (due to the patients wish); 3320 g; 40th week; female; 10 | Rotation- plasty | 6 months postpartum |
IV | Pain which appeared in the period between the 30th to the 33th week of pregnancya | 1st in 2004 | Upper ankle joint (left); 3x2,7,x1,5 | Synovial sarcoma | G2; pT1b ◊ | - | Vaginal delivery; 3070 g; 38th week; female; 10 | En-bloc resection | 4,5 months postpartum |
V | Pain noticed 32th week of pregnancy | 2nd in 2002 | Femoral head (left); 16x9x8 after neoadjuvant chemotherapy | Osteosarcoma chondrobl. | G3; pT2, pNX, pM1 (Oss) | Increasing pain until treatment | Vaginal delivery; 3450 g; 41th week; female; 9 | Hemi- pelvectomy | 4 months postpartum |
VI | Pain which occurred between the 12th-16th week of pregnancya | 4th in 2007 [spontaneous abortion] | Thigh med. compart. (left); 10,5x9,5x8 | Synovial sarcoma | G2 (3/1/1); pT2b, pNX ◊ | Increasing tumescence in pregnancy | Spontaneous abortion; weight unknown; patient could not remember week of abortion and did not want to know the sex of the fetus; dead | Resection | c |
VII | Pain and growing mass both noticed in the 30th week of pregnancy | 2nd in 2009 | Thigh dorsal (right); 10x9x5 | Liposarcoma | G2; pT2a ∆ | Increasing tumor volume in pregnancy | vaginal delvery; 3200 g; 41th week; female; healthy; − | Resection | 4 months postpartum |
VIII | Pain, tumescencec | 3rd in 2003 | Foot (right); several sarcoma focuses | Fibrosarcoma | G1; pT2b | Increasing pain and tumescence until 3rd treatment | vaginal delivery; 3500 g; 40th week; male; 10 | 3 times amputation | gestational age of 24, 27 and 28 weeks |