Table 1 Baseline characteristics of the study population
Premenopause | Menopausal transition | Postmenopause | P-value | ||
|---|---|---|---|---|---|
Variable | (n=809) | Early (n=317) | Late (n=414) | (n=661) | |
Age, year | 46.8±2.5 | 47.5±2.4 | 49.6±2.8 | 52.2±3.1 | <.001 |
BMI, kg/m2 | 23.0±3.1 | 22.8±3.0 | 23.0±3.1 | 23.4±3.1 | 0.006 |
WC, cm | 78.3±7.8 | 78.2±7.2 | 78.9±8.0 | 80.1±8.0 | <.001 |
Smoking, n (%) | 24(4.2) | 6(2.7) | 10(3.5) | 19(4.3) | 0.734 |
SBP, mmHga | 102.9±12.5 | 102.6±11.3 | 106.0±13.7 | 105.2±12.2 | <.001 |
DBP, mmHga | 66.9±9.7 | 66.2±8.7 | 69.1±10.3 | 68.2±9.3 | <.001 |
Hypertension, n (%) | |||||
Normal | 683(84.6) | 261(82.3) | 305(74.4) | 490(74.5) | <.001 |
Prehypertension | 71(8.8) | 31(9.8) | 49(12.0) | 73(11.1) | |
Hypertension | 53(6.6) | 25(7.9) | 56(13.7) | 95(14.4) | |
Menopause symptoms, score (0–6) | |||||
Vasomotor | 0.5±0.9 | 0.7±1.0 | 1.1±1.4 | 1.6±1.6 | <.001 |
Psychosocial | 1.1±1.1 | 1.4±1.2 | 1.6±1.3 | 1.8±1.4 | <.001 |
Physical | 1.5±1.0 | 1.8±1.1 | 1.9±1.2 | 2.0±1.2 | <.001 |
Sexual | 1.1±1.3 | 1.5±1.5 | 1.8±1.7 | 2.5±1.9 | <.001 |
Glucose, mg/dL | 95.1±13.6 | 94.2±15.7 | 96.5±16.9 | 96.8±15.1 | 0.032 |
HDL-cholesterol, mg/dL | 63.1±14.7 | 63.8±14.8 | 64.5±15.7 | 62.3±15.7 | 0.100 |
LDL-cholesterol, mg/dL | 117.3±28.3 | 118.1±29.0 | 128.2±33.3 | 131.9±32.1 | <.001 |
Triglycerides, mg/dL | 90.2±53.9 | 93.0±56.1 | 97.5±58.9 | 102.2±54.6 | <.001 |
HOMA-IR | 1.5±1.1 | 1.4±0.9 | 1.3±1.0 | 1.5±1.1 | 0.121 |
GGT, U/L | 19.1±24.7 | 18.0±14.6 | 20.9±22.3 | 25.1±30.1 | <.001 |
FreeT3, pg/mL | 2.8±0.4 | 2.9±0.3 | 2.9±0.4 | 3.0±0.4 | <.001 |
Uric acid, mg/dL | 4.1±0.8 | 4.0±0.8 | 4.3±0.9 | 4.4±0.9 | <.001 |