Table 2 Characteristics of IVF-ICSI treatment according to body mass index (BMI)
From: Does obesity have detrimental effects on IVF treatment outcomes?
BMI | |||||
|---|---|---|---|---|---|
18.5–24.9 | 25.0–29.9 | ≥30.0 | P | ||
(n = 164) | (n = 70) | (n = 64) | |||
Gonadotropin dose, | |||||
Total for cycle (IU) | 1859 ± 1065a | 2015 ± 968a,b | 2455 ± 1343b | <0.001 | |
Per retrieved oocyte (IU) | 256 ± 429 | 249 ± 336 | 249 ± 192 | 0.112 | |
Per M2 oocyte (IU) | 338 ± 557a | 313 ± 358a | 436 ± 434b | 0.017 | |
Per embryo suitable for transfer (IU) | 785 ± 1039 | 661 ± 562 | 806 ± 749 | 0.087 | |
Duration of stimulation (days) | 8.7 ± 1.8a | 8.9 ± 1.9a,b | 9.8 ± 2.4b | 0.008 | |
Ovarian stimulation protocol | |||||
Long protocol | 99 (60.4) | 39 (55.7) | 36 (56.2) | 0.334 | |
Short (antagonist) protocol | 55 (33.5) | 26 (37.2) | 24 (37.5) | 0.256 | |
Micro dose protocol | 10 (6.1) | 5 (7.1) | 4 (6.3) | 0.134 | |
No. of retrieved oocytes | 12.3 ± 6.2 | 12.8 ± 6.1 | 13.2 ± 7.3 | 0.821 | |
No. of MII oocytes | 9.5 ± 5.3 | 9.2 ± 5.4 | 9.0 ± 6.9 | 0.329 | |
Proportion of oocytes fertilized (%) | 75.6 ± 20.1 | 79.1 ± 20.3 | 75.4 ± 22.1 | 0.215 | |
No. of embryos suitable for transfer | 4.2 ± 3.0 | 4.5 ± 3.3 | 3.6 ± 2.9 | 0.160 | |
Extended culture | 55 (34.6) | 27 (39.1) | 20 (33.9) | 0.591 | |
Canceled cycles | 5 (3.0) | 2 (2.9) | 5 (7.8) | 0.119 | |
No. of transferred embryos | SET | 130 (81.8) | 54 (79.4) | 46 (78.0) | 0.416 |
DET | 29 (18.2) | 14 (20.6) | 13 (22.0) | ||
Pregnancy outcome* | |||||
Implantation | 62 (39.0) | 26 (38.2) | 21 (35.6) | 0.755 | |
Biochemical pregnancy | 6 (3.8) | 4 (5.8) | 1 (1.7) | 0.483 | |
Ectopic pregnancy | 2 (1.3) | 0 (0.0) | 1 (1.7) | 0.595 | |
Clinical pregnancy | 52 (32.7) | 22 (32.4) | 18 (30.5) | 0.953 | |
Spontaneous abortion | 6 (3.8) | 3 (4.3) | 3 (5.1) | 0.909 | |
Ongoing pregnancy | 46 (28.9) | 19 (27.9) | 15 (25.4) | 0.874 | |