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Table 2 Characteristics of IVF-ICSI treatment according to body mass index (BMI)

From: Does obesity have detrimental effects on IVF treatment outcomes?

  BMI
  18.5–24.9 25.0–29.9 ≥30.0 P
  (n = 164) (n = 70) (n = 64)
Gonadotropin dose,     
Total for cycle (IU) 1859 ± 1065a 2015 ± 968a,b 2455 ± 1343b <0.001
Per retrieved oocyte (IU) 256 ± 429 249 ± 336 249 ± 192 0.112
Per M2 oocyte (IU) 338 ± 557a 313 ± 358a 436 ± 434b 0.017
Per embryo suitable for transfer (IU) 785 ± 1039 661 ± 562 806 ± 749 0.087
Duration of stimulation (days) 8.7 ± 1.8a 8.9 ± 1.9a,b 9.8 ± 2.4b 0.008
Ovarian stimulation protocol     
Long protocol 99 (60.4) 39 (55.7) 36 (56.2) 0.334
Short (antagonist) protocol 55 (33.5) 26 (37.2) 24 (37.5) 0.256
Micro dose protocol 10 (6.1) 5 (7.1) 4 (6.3) 0.134
No. of retrieved oocytes 12.3 ± 6.2 12.8 ± 6.1 13.2 ± 7.3 0.821
No. of MII oocytes 9.5 ± 5.3 9.2 ± 5.4 9.0 ± 6.9 0.329
Proportion of oocytes fertilized (%) 75.6 ± 20.1 79.1 ± 20.3 75.4 ± 22.1 0.215
No. of embryos suitable for transfer 4.2 ± 3.0 4.5 ± 3.3 3.6 ± 2.9 0.160
Extended culture 55 (34.6) 27 (39.1) 20 (33.9) 0.591
Canceled cycles 5 (3.0) 2 (2.9) 5 (7.8) 0.119
No. of transferred embryos SET 130 (81.8) 54 (79.4) 46 (78.0) 0.416
DET 29 (18.2) 14 (20.6) 13 (22.0)  
Pregnancy outcome*     
Implantation 62 (39.0) 26 (38.2) 21 (35.6) 0.755
Biochemical pregnancy 6 (3.8) 4 (5.8) 1 (1.7) 0.483
Ectopic pregnancy 2 (1.3) 0 (0.0) 1 (1.7) 0.595
Clinical pregnancy 52 (32.7) 22 (32.4) 18 (30.5) 0.953
Spontaneous abortion 6 (3.8) 3 (4.3) 3 (5.1) 0.909
Ongoing pregnancy 46 (28.9) 19 (27.9) 15 (25.4) 0.874
  1. Data are presented as mean ± standard deviation or n (%). BMI body mass index, MII metaphase 2, SET single embryo transfer, DET double embryo transfer, ns non significant (p <0.05)
  2. Values across a row with different superscripts (a-b)indicate significant difference between pregnancy outcome categories (p <0.017), and values across an individual row with matching superscripts (a-b)indicate no significant difference between pregnancy outcome categories. *Data for pregnancy outcomes are expressed per embryo transfer