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Table 2 Final diagnoses obtained from each group (IFF/Fiocruz-INCA, RJ, Brazil, 2006–2012)

From: Preinvasive and invasive disease in women with cytological diagnosis of high-grade lesion and high-grade lesion cannot exclude microinvasion

 

Pap smear diagnosis n (%)

Total

 

Final diagnosisa

HSIL microh

HSILc

 

p-value

Negative

0 (0)

24 (12.8)

24 (10.2)

0.005

LSILb

2 (4.3)

28 (14.9)

30 (12.8)

0.052

HSILc

15 (31.9)

112 (59.6)

127 (54)

<0.001

AISd

0 (0)

2 (1.1)

2 (0.9)

1.000

Microinvasive lesione

6 (12.8)

10 (5.3)

16 (6.8)

0.070

Invasive lesionf

19 (40.4)

9 (4.8)

28 (11.9)

<0.001

Adenocarcinomag

5 (10.6)

3 (1.6)

8 (3.4)

0.009

Total (%)

47 (100)

188 (100)

235 (100)

 
  1. aDiagnoses obtained at the end of investigation considering histopathological specimens. Negative cases were based on absence of visible colposcopic findings and two negative cytopathologic exams with a minimum of six-month intervals
  2. bLow-grade squamous intraepithelial lesion (includes cytopathic effect by HPV and CIN 1)
  3. cHigh-grade squamous lesion (includes CIN 2 and CIN 3)
  4. dAdenocarcinoma in situ
  5. eMicroinvasive squamous carcinoma of the cervix
  6. fInvasive squamous carcinoma of the cervix
  7. gInvasive squamous adenocarcinoma of the cervix
  8. hHigh-grade intraepithelial lesion cannot exclude microinvasion