Preinvasive and invasive disease in women with cytological diagnosis of high-grade lesion and high-grade lesion cannot exclude microinvasion

Table 4 Prevalence of invasive disease by study group (IFF/Fiocruz-INCA, RJ, Brazil, 2006–2012)

Final diagnosis^a	Invasive lesion^b	Absence of invasive lesion^c	Total n (%)	Prevalence Ratio (PR) (CI 95 %)
Pap smear diagnosis
HSIL-micro^d	30	17	47	2.4 (1.7 – 3.6)
HSIL^e	22	166	188	<0.001
Total	52	183	235	-

^aRecategorized diagnoses obtained at the end of investigation considering histopathological specimens. Negative cases were based on absence of visible colposcopic findings and two negative cytopathologic exams with a minimum of six-month intervals
^bIncludes microinvasive squamous carcinoma of the cervix
^cIncludes negatives, CIN 1, 2 or 3, or AIS
^dHigh-grade intraepithelial lesion cannot exclude microinvasion
^eHigh-grade intraepithelial lesion

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