Three-dimensional ultrasonography and power Doppler for discrimination between benign and malignant endometrium in premenopausal women with abnormal uterine bleeding

Table 3 Diagnostic performance of ultrasound markers

Parameter	ET	EV	Endometrial VI	Endometrial VFI
Cutoff value	19 mm	8 cm³	0.81 %	0.22
AUC	0.73	0.81	0.88	0.67
Sensitivity (%)	80	90	90	60
Specificity (%)	72	79	88	68
PPV (%)	30	39	53	23
NPV (%)	96	98	98	92
LR+	2.86	4.29	7.50	1.88
LR−	0.28	0.13	0.11	0.59

ET endometrial thickness, EV endometrial volume, VI vascularization index, VFI vascularization flow index, AUC area under receiver-operating characteristics (ROC) curve, PPV positive predictive value, NPV negative predictive value, LR+ likelihood ratio of a positive test, LR likelihood ratio of a negative test