From: Quality of life among post-menopausal women due to oxidative stress boosted by dysthymia and anxiety
Parameter | Premenopausal women (n = 101) | Postmenopausal women (n = 101) | p value |
---|---|---|---|
Biochemical -hematologic parameters | |||
Hemoglobin (g/dL) | 14.0 ± 1.5 | 14.6 ± 1.4 | 0.002 |
Hematocrit (%) | 43 ± 3.9 | 45 ± 3.9 | 0.003 |
Erythrocytes (X1012/L) | 4.6 ± 0.5 | 4.8 ± 0.7 | 0.034 |
Total leukocytes (X109/L) | 6431 ± 1573 | 6071 ± 1192 | 0.070 |
Glucose (mmol/L) | 5.6 ± 2.5 | 5.2 ± 1.8 | 0.773 |
Urea (mmol/L) | 9.6 ± 2.1 | 10.4 ± 2.5 | 0.085 |
Uric acid (μmol/L) | 274 ± 77 | 280 ± 77 | 0.735 |
Creatinine (μmol/L) | 72 ± 15 | 72 ± 12 | 0.848 |
Cholesterol (mmol/L) | 5.6 ± 0.9 | 5.9 ± 1.1 | 0.057 |
Triglycerides (mmol/L) | 2.0 ± 1.0 | 2.1 ± 1.1 | 0.552 |
HDL-c (mmol/L) | 1.5 ± 0.4 | 1.6 ± 0.4 | 0.832 |
Estrogen (pg/mL) | 101.7 ± 71.5 | 12.3 ± 6.2 | <0.0001 |
FSH (mIU/mL) | 10.7 ± 12.2 | 55.2 ± 26.1 | <0.0001 |
Anthropometric and blood pressure measurement | |||
BMI (kg/m2) | 28.34 ± 4.4 | 28.82 ± 4.2 | 0.427 |
Systolic blood pressure (mm Hg) | 123 ± 16 | 126 ± 15 | 0.208 |
Diastolic blood pressure /mm Hg) | 83 ± 9.0 | 85 ± 8.2 | 0.122 |
Oxidative stress markers | |||
Lipoperoxides (μmol/L) | 0.334 ± 0.05 | 0.356 ± 0.05 | 0.005 |
Superoxide dismutase (U/g Hb) | 1.23 ± 0.17 | 1.18 ± 0.13 | 0.023 |
Glutathione peroxidase (U/g Hb) | 56.2 ± 16.9 | 50.3 ± 14.5 | 0.010 |
Total antioxidant status (μmol/L) | 1020 ± 166 | 1052 ± 185 | 0.215 |
SOD/GPx ratio | 0.023 ± 0.007 | 0.025 ± 0.007 | 0.061 |
Antioxidant gap (μmol/L) | 292 ± 170 | 305 ± 191 | 0.616 |