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Table 4 Sulaimaniyah ER and HER2 breast cancer subtypes by age groups, Kurdish and Arabic

From: Breast cancer in Iraq is associated with a unimodally distributed predominance of luminal type B over luminal type A surrogates from young to old age

Age (years)

ER+/HER2-

ER+/HER2+

ER-/HER2+

Triple-

Luminal A

Luminal B

20–39

97

19

30

28

23

67

40–49

189

33

30

31

64

96

50–59

146

18

27

26

39

57

60+

110

9

22

22

30

48

All (%)

542 (64.8)

79 (9.4)

109 (13.0)

107 (12.8)

156 (27.4)*

268 (46.8)*

Ave age

49.7 ± 11.7

46.2 ± 11.0a

47.3 ± 10.4

48.8 ± 13.2

49.7 ± 10.7b

47.6 ± 11.3

Ki67

26.1 ± 18.6 c

39.9 ± 21.0

43.1 ± 23.0

56.6 ± 26.5 c

11.6 ± 5.0

37.9 ± 18.4

  1. Legend: *Luminal A and luminal B are derived from ER+/HER2- and ER+/HER2+ tumors that had Ki67 testing with the percentages being extrapolated to the sum of all subtypes. The number of luminal A and Luminal B tumors (n = 424) does not correspond to the number of ER+/HER2- and ER+/HER2+ tumors (n = 621), because not all of the later had Ki67 testing. The age of ER+/HER2+ patients is significantly different than ER+/HER2- patients (P < 0.01)a. The age of luminal A patients is significantly different than luminal B patients (P = 0.04)b. The Ki67 of ER+/HER2- and triple- breast cancers are significantly different than other subtypes (P < 0.001)c