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Table 3 Exposure of pregnant women to medical devices containing PVC plasticizers during their hospital stay

From: Exposure of hospitalised pregnant women to plasticizers contained in medical devices

 

Total

N = 168 (%)

Pathology group

n = 52 (%)

Pathology and delivery group

n = 23 (%)

Delivery group

n = 93 (%)

p-value

Exposure at least to one MD with PVC

151 (90)

35 (67%)

23 (100)

93 (100)

-

Exposure at least to one MD with PVC according to the predominantly plasticizera

DEHP

0

0

0

0

-

DiNPb

124 (74)

25 (48)

21 (91)

78 (84)

< 0.001

TOTMc

123 (73)

21 (40)

19 (83)

83 (89)

< 0.001

DINCHd

6 (4)

6 (11.5)

0

0

-

  1. aData based on gas chromatography-mass spectrometry analysis; during their hospital stay, women could be exposed to different MDs containing various plasticizers
  2. bType of MD containing DiNP: simple infusion set
  3. cType of MDs containing TOTM: multi-access infusion set, epidural infusion set and extension tubes
  4. dType of MD containing DINCH: flow regulator; all women exposed to at least one MD containing DINCH had been admitted for pregnancy-related vomiting episodes
  5. Abbreviations: DEHP di-(2-ethylhexyl) phthalate, DINCH di(isononyl)-cyclohexane-1,2-dicarboxilic acid, DiNP di-(isononyl) phthalate, MD medical device, PVC polyvinyl chloride, TOTM tri-octyltrimellitate