| Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
OR | 95% CI for OR | p | OR | 95% CI for OR | p | |
Age at diagnosis | 0.529 | 0.365–0.766 | 0.0007 | 0.459 | 0.309–0.683 | 0.0001 |
  ≤ 35 | 1 | - | - |  |  |  |
 36–40 | 0.767 | 0.316–1.861 | 0.5575 |  |  | |
 41–45 | 0.332 | 0.149–0.741 | 0.0072 |  |  | |
>/= 1 children before breast cancer diagnosis | 0.751 | 0.428–1.315 | 0.3160 |  |  | |
1st degree relative with breast cancer | 1.425 | 0.488–4.167 | 0.5173 |  |  | |
ER positive | 0.975 | 0.566–1.682 | 0.9282 |  |  | |
PR positive | 1.211 | 0.726–2.022 | 0.4632 |  |  | |
HER2 over-expression | 1.032 | 0.538–1.981 | 0.9238 |  |  | |
Received adjuvant radiotherapy | 1.352 | 0.812–2.250 | 0.2466 |  |  | |
Received adjuvant taxane-containing chemotherapy | 1.903 | 1.073–3.374 | 0.0278 | 2.041 | 1.127–3.696 | 0.0186 |
Duration of adjuvant chemotherapy >64 days | 1.904 | 1.137–3.189 | 0.0143 |  |  |  |
Received corticosteroid premedication during chemotherapy | 1.605 | 0.608–4.237 | 0.3390 |  |  | |
Received adjuvant tamoxifen therapy | 1.366 | 0.778–2.398 | 0.2781 |  |  | |
Received adjuvant trastuzumab | 0.969 | 0.227–4.140 | 0.9660 |  |  | |
Use of traditional Chinese medicine since diagnosis | 1.303 | 0.758–2.239 | 0.3384 |  |  | |
Education | 1.299 | 0.850–1.987 | 0.2271 |  |  |  |
 Primary school | 1 | - | - |  |  | |
 Secondary school | 1.447 | 0.757–2.766 | 0.2642 |  |  | |
 Tertiary school + Higher qualification | 1.669 | 0.718–3.878 | 0.2336 |  |  | |
Employment- Working | 0.954 | 0.579–1.572 | 0.8531 |  |  | |
Family income </= HK$ 25,000 | 1.388 | 0.832–2.315 | 0.2097 |  |  | |
Ever Smoker | 0.374 | 0.103–1.357 | 0.1348 |  |  | |
Ever excessive alcohol intake (>2Â units/day) | - | - | 0.9868 | Â | Â | |
Chemotherapy-related amenorrhea | 2.375 | 1.034–5.435 | 0.0414 | 3.472 | 1.395–8.621 | 0.0074 |
Post/peri- menopausal at study entry | 0.666 | 0.408–1.085 | 0.1023 |  |  |  |
Age at study entry | 0.593 | 0.429–0.819 | 0.0015 |  |  | |
  ≤ 40 | 1 | - |  |  |  | |
 41–45 | 0.755 | 0.297–1.923 | 0.5561 |  |  | |
 46–50 | 0.467 | 0.198–1.102 | 0.0822 |  |  | |
  > 50 | 0.185 | 0.059–0.580 | 0.0038 |  |  |