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Table 2 Univariate and multivariate analysis on factors associated with weight gain >2%, by stepwise logistic regression

From: Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy

 

Univariate analysis

Multivariate analysis

OR

95% CI for OR

p

OR

95% CI for OR

p

Age at diagnosis

0.529

0.365–0.766

0.0007

0.459

0.309–0.683

0.0001

  ≤ 35

1

-

-

   

 36–40

0.767

0.316–1.861

0.5575

  

 41–45

0.332

0.149–0.741

0.0072

  

>/= 1 children before breast cancer diagnosis

0.751

0.428–1.315

0.3160

  

1st degree relative with breast cancer

1.425

0.488–4.167

0.5173

  

ER positive

0.975

0.566–1.682

0.9282

  

PR positive

1.211

0.726–2.022

0.4632

  

HER2 over-expression

1.032

0.538–1.981

0.9238

  

Received adjuvant radiotherapy

1.352

0.812–2.250

0.2466

  

Received adjuvant taxane-containing chemotherapy

1.903

1.073–3.374

0.0278

2.041

1.127–3.696

0.0186

Duration of adjuvant chemotherapy >64 days

1.904

1.137–3.189

0.0143

   

Received corticosteroid premedication during chemotherapy

1.605

0.608–4.237

0.3390

  

Received adjuvant tamoxifen therapy

1.366

0.778–2.398

0.2781

  

Received adjuvant trastuzumab

0.969

0.227–4.140

0.9660

  

Use of traditional Chinese medicine since diagnosis

1.303

0.758–2.239

0.3384

  

Education

1.299

0.850–1.987

0.2271

   

 Primary school

1

-

-

  

 Secondary school

1.447

0.757–2.766

0.2642

  

 Tertiary school + Higher qualification

1.669

0.718–3.878

0.2336

  

Employment- Working

0.954

0.579–1.572

0.8531

  

Family income </= HK$ 25,000

1.388

0.832–2.315

0.2097

  

Ever Smoker

0.374

0.103–1.357

0.1348

  

Ever excessive alcohol intake (>2 units/day)

-

-

0.9868

  

Chemotherapy-related amenorrhea

2.375

1.034–5.435

0.0414

3.472

1.395–8.621

0.0074

Post/peri- menopausal at study entry

0.666

0.408–1.085

0.1023

   

Age at study entry

0.593

0.429–0.819

0.0015

  

  ≤ 40

1

-

   

 41–45

0.755

0.297–1.923

0.5561

  

 46–50

0.467

0.198–1.102

0.0822

  

  > 50

0.185

0.059–0.580

0.0038

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