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Table 3 Univariate and multivariate analyses on factors associated with hypertension at study entry, by stepwise logistic regression

From: Profiles of lipids, blood pressure and weight changes among premenopausal Chinese breast cancer patients after adjuvant chemotherapy

  Univariate analysis Multivariate analysis
OR 95% CI for OR p OR 95% CI for OR p
Age at diagnosis 1.243 0.869–1.779 0.2343    
  ≤ 35 1 -    
 36–40 1.000 0.429–2.331 1.0000   
 41–45 1.417 0.658–3.050 0.3727   
>/= 1 children before breast cancer diagnosis 1.291 0.715–2.332 0.3695   
1st degree relative with breast cancer 0.926 0.316–2.715 0.8885   
ER positive 0.517 0.298–0.895 0.0186 0.552 0.311–0.980 0.0423
PR positive 0.712 0.419–1.213 0.2115    
HER2 over-expression 1.187 0.610–2.309 0.6134   
Received adjuvant radiotherapy 0.866 0.508–1.477 0.5984   
Received adjuvant taxane-containing chemotherapy 0.887 0.501–1.568 0.6790   
Duration of adjuvant chemotherapy >64 days 0.828 0.483–1.420 0.4928   
Received corticosteroid premedication during chemotherapy 1.046 0.410–2.667 0.9251   
Received adjuvant tamoxifen therapy 0.557 0.313–0.990 0.0462   
Received adjuvant trastuzumab 1.352 0.316–5.789 0.6846   
Use of traditional Chinese medicine since diagnosis 0.947 0.542–1.655 0.8486   
Education 0.789 0.507–1.228 0.2936   
 Primary school 1 - -   
 Secondary school 0.907 0.461–1.787 0.7784   
 Tertiary school + Higher qualification 0.609 0.246–1.509 0.2840   
Employment- Working 0.815 0.485–1.369 0.4397   
Family income </= HK$ 25,000 0.753 0.441–1.287 0.3000   
Ever Smoker 0.271 0.033–2.198 0.2214   
Ever excessive alcohol intake (>2 units/day) - - 0.9877   
Chemotherapy-related amenorrhea 0.778 0.329–1.838 0.5665   
Post/peri- menopausal at study entry 0.930 0.559–1.548 0.7808   
Weight gain >2% at study entry 1.095 0.644–1.864 0.7371   
Total Cholesterol >/= 5.2 mmol/L 1.475 0.865–2.516 0.1534   
LDL Cholesterol >/= 2.6 mmol/L 1.762 1.027–3.021 0.0396   
HDL Cholesterol </= 1.0 mmol/L 1.842 0.700–4.850 0.2160   
Triglyceride >/=1.7 mmol/L 1.568 0.867–2.836 0.1364   
Overweight/obese at study entry 2.751 1.608–4.707 0.0002 2.723 1.568–4.728 0.0004
Age at study entry 1.173 0.852–1.614 0.3273    
  ≤ 40 1 -    
 41–45 1.929 0.738–5.037 0.1799   
 46–50 1.774 0.720–4.371 0.2126   
  > 50 2.057 0.623–6.794 0.2367   
  1. Hypertension defined as systolic blood pressure >/= 140 mmHg, or diastolic blood pressure >/=90 mmHg