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Table 1 Characteristics of the groups

From: Therapeutic comparison between treatments for Vulvar Lichen Sclerosus: study protocol of a randomized prospective and controlled trial

Group

Number

Treatment

Parameters

GC

20

Corticosteroid over the whole vulva

Clobetasol propionate 0.05% ointment applied once daily at a dose of 1 g/application (1 g sachets) for 4 weeks

GPDT

20

Localized photodynamic therapy at 8 points of the vulva

Methylene blue 0.01% intralesional + lidocaine 2%, λ = 660 ± 10 nm, P = 100 mW, I = 510 mW/cm2, E = 4 J, RE = 20 J/cm2, t = 40 s, once a week for 4 weeks

GPBM

20

Localized photobiomodulation at 8 points of the vulva

The same parameters as for GPDT, except for the methylene blue, once a week for 4 weeks

  1. Laser parameters: λ wavelength, P power, I irradiance, E energy, RE radiant exposure, t exposure time. Laser: Photon Laser III (DMC®, São Carlos/SP, Brazil). Methylene blue: Chimiolux 10 (DMC®, São Carlos/SP, Brazil). Clobetasol propionate: Drogaderma®, São Paulo/SP, Brazil)