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Table 2 Receiver-operating characteristic (ROC) curve analysis for the discrimination between patients with unexplained infertility and control group

From: AlphaVBeta3 Integrin expression within uterine endometrium in unexplained infertility: a prospective cohort study

ROC Index Endometrial thickness Subendometrial RI ανβ3-integrin score
AUC 0.966 0.918 0.880
95% CI of AUCŦ 0.932 to 1.0 0.854 to 0.981 0.799 to 0.961
P value* <0.0001 <0.0001 <0.0001
Youden index J 0.80 0.71 0.74
Cut-off criterion ≤7 mm >0.65 Score 0
Sensitivity (%) 82.9 74.3 74.3
95% CI of sensitivity 66.4–93.4 56.7–87.5 56.7–87.5
Specificity 97.1 97.1 100.0
95% CI of Specificity 85.1–99.9 85.1–99.9 90.0–100.0
Positive predictive value (PPV) % 96.7 96.3 100.0
95% CI of PPV 82.8–99.9 81.0–99.9 86.8–100.0
Negative predictive value (NPV) % 85.0 79.1 79.5
95% CI of NPV 70.2–94.3 64.0–90.0 64.7–90.2
  1. ŦAUC, area under the curve, PPV, positive predictive value; NPV, negative predictive value
  2. *DeLong method