Skip to main content

Table 2 Receiver-operating characteristic (ROC) curve analysis for the discrimination between patients with unexplained infertility and control group

From: AlphaVBeta3 Integrin expression within uterine endometrium in unexplained infertility: a prospective cohort study

ROC Index

Endometrial thickness

Subendometrial RI

ανβ3-integrin score

AUC

0.966

0.918

0.880

95% CI of AUCŦ

0.932 to 1.0

0.854 to 0.981

0.799 to 0.961

P value*

<0.0001

<0.0001

<0.0001

Youden index J

0.80

0.71

0.74

Cut-off criterion

≤7 mm

>0.65

Score 0

Sensitivity (%)

82.9

74.3

74.3

95% CI of sensitivity

66.4–93.4

56.7–87.5

56.7–87.5

Specificity

97.1

97.1

100.0

95% CI of Specificity

85.1–99.9

85.1–99.9

90.0–100.0

Positive predictive value (PPV) %

96.7

96.3

100.0

95% CI of PPV

82.8–99.9

81.0–99.9

86.8–100.0

Negative predictive value (NPV) %

85.0

79.1

79.5

95% CI of NPV

70.2–94.3

64.0–90.0

64.7–90.2

  1. ŦAUC, area under the curve, PPV, positive predictive value; NPV, negative predictive value
  2. *DeLong method