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Table 3 Least squares (LS) means scoresa (95% Confidence intervals, CIs) of HRQoL according to quartiles of Healthy dietary pattern in breast cancer survivors

From: Dietary pattern and health-related quality of life among breast cancer survivors

  

Quartiles of the Healthy dietary pattern

 

Variables

N (=232)

Quartile 1

Quartile 2

Quartile 3

Quartile 4

P for trend

EORTC QLQ - C30

 Global health status/QoL

220

40.41 (28.37 - 57.55)

37.47 (27.10 - 51.81)

39.93 (28.92 - 55.14)

30.00 (20.83 - 43.21)

0.31

Functioning

 Physical Functioning

228

76.21 (67.82 - 85.65)

79.02 (71.09 - 87.85)

77.80 (69.85 - 86.65)

71.45 (63.52 - 80.37)

0.45

 Role Functioning

229

62.82 (49.32 - 80.02)

77.50 (61.80- 97.17)

69.47 (55.05 - 87.66)

65.77 (51.12 - 84.62)

0.84

 Emotional Functioning

230

76.24 (63.16 - 92.04)

72.09 (60.45 - 85.96)

60.42 (50.51 - 72.26)

71.77 (58.99 - 87.32)

0.31

 Cognitive Functioning

230

74.53 (65.00 - 85.44)

78.52 (69.10 - 89.22)

73.09 (64.18 - 83.23)

70.66 (61.28 - 81.47)

0.48

 Social Functioning

230

57.8 (45.69 - 73.12)

63.28 (50.80 - 78.84)

60.55 (48.42 - 75.72)

62.67 (49.05 - 80.05)

0.66

Symptom

 Fatigue

229

27.26 (19.48 - 38.15)

20.26 (14.88 - 27.58)

22.61 (16.52 - 30.94)

23.51 (16.68 - 33.13)

0.55

 Nausea and vomiting

230

4.00 (2.48 - 6.44)

2.24 (1.44 - 3.49)

3.71 (2.36 - 5.83)

3.17 (1.93 - 5.21)

0.73

 Pain

229

9.84 (5.80 - 16.71)

6.13 (3.77 - 9.97)

11.13 (6.79 - 18.24)

10.64 (6.20 - 18.28)

0.53

 Dyspneab,c

228

8.86 (5.05 - 15.52)

4.21 (2.52 - 7.03)

4.75 (2.82 - 8.01)

2.87 (1.62 - 5.08)

0.005

 Insomniab,c

228

11.46 (6.59 - 19.95)

12.11 (7.28 - 20.15)

20.41 (12.15 - 34.26)

29.77 (16.87 - 52.51)

0.005

 Loss of appetite

228

3.00 (1.74 - 5.15)

3.66 (2.23 - 6.02)

2.65 (1.60 - 4.39)

3.32 (1.91 - 5.79)

0.99

 Constipation

228

4.25 (2.40 - 7.54)

5.69 (3.36 - 9.63)

7.01 (4.10 - 11.99)

4.18 (2.32 - 7.50)

0.78

 Diarrhea

230

3.04 (1.82 - 5.08)

2.47 (1.53 - 3.99)

2.76 (1.70 - 4.51)

1.79 (1.05 - 3.05)

0.18

 Financial impact

230

7.34 (4.12 - 13.07)

4.51 (2.63 - 7.74)

9.47 (5.47 - 16.40)

9.61 (5.27 - 17.53)

0.27

EORTC QLQ-BR23

 Functioning

  Body image

229

40.11 (27.32 - 58.88)

33.23 (23.21 - 47.59)

40.56 (28.06 - 58.62)

28.18 (18.89 - 42.03)

0.30

  Sexual functioning

216

2.83 (1.62 - 4.92)

3.89 (2.32 - 6.52)

3.93 (2.33 - 6.65)

3.94 (2.20 - 7.08)

0.33

  Future perspective

229

26.93 (15.91 - 45.58)

20.85 (12.74 - 34.10)

21.67 (13.08 - 35.90)

15.43 (8.92 - 26.70)

0.14

 Symptom

  Systematic therapy side effects

230

23.34 (17.37 - 31.37)

15.01 (11.39 - 19.79)

22.47 (16.96 - 29.76)

25.97 (19.09 - 35.33)

0.39

  Breast symptoms

230

12.10 (7.66 - 19.11)

6.96 (4.54 - 10.68)

10.50 (6.80 - 16.22)

12.11 (7.52 - 19.49)

0.84

  Arm symptoms

230

20.54 (13.59 - 31.03)

18.25 (12.41 - 26.84)

21.70 (14.65 - 32.12)

31.48 (20.48 - 48.39)

0.13

  Upset by hair loss

151

14.15 (6.70 - 29.89)

32.78 (15.61 - 68.82)

23.84 (12.30 - 46.18)

34.49 (16.45 - 72.32)

0.11

  1. LS means least squares means, 95% CI 95% confidence interval, HRQoL health-related quality of life, EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30, BR23 breast cancer module 23
  2. aAdjusted for age at diagnosis (year; continuous), body mass index at diagnosis (kg/m2; continuous), energy intake (kcal/d; continuous), marital status (married or cohabitation, others), education level (high school or below, college or above), physical activity (MET-hr/wk.; continuous), breast cancer stage at diagnosis (I,II,III), time since surgery (months; continuous) and menopausal status at diagnosis (premenopausal, postmenopausal status)
  3. bP value for comparing top with bottom quintiles < 0.05
  4. cFalse Discovery Rate (FDR) < 0.1