Skip to main content

Advertisement

Table 1 Basic characteristics of all studies included in this meta-analysis

From: Aldehyde dehydrogenase serves as a biomarker for worse survival profiles in ovarian cancer patients: an updated meta-analysis

Author Country Year Sample size Cutoff Cutoff class Survival HR (95% CI) HR HR_low HR_high Analysis
Yu China 2017 207 IRS ≥ 3 IRS OS 1.86 (1.16–2.98) 1.86 1.16 2.98 Multivariate
Huang Norway 2015 248 IRS ≥ 7 IRS OS 0.913 (0.735–1.134) 0.913 0.735 1.134 Multivariate
       PFS 1.023 (0.756–1.165) 1.023 0.756 1.165 Multivariate
Mizuno Japan 2015 81 ≥10% low OS 1.765 (0.874–2.984) 1.765 0.874 2.984 Univariate
       PFS 2.134 (1.103–3.654) 2.134 1.103 3.654 Univariate
Madhuchhanda USA 2017 124 ≥5% low OS 1.127 (0.903–1.564) 1.127 0.903 1.564 Univariate
       PFS 1.097 (0.874–1.645) 1.097 0.874 1.645 Univariate
Ruscito Germany 2017 112 IRS ≥ 2 IRS OS 1.707 (1.012–2.881) 1.707 1.012 2.881 Multivariate
Chen China 2015 80 ≥10% low OS 2.684 (1.149–6.249) 2.684 1.149 6.249 Multivariate
Sun China 2015 100 IRS ≥ 9 IRS PFS 2.574 (1.297–5.638) 2.574 1.297 5.638 Univariate
Chang USA 2009 440 > 20% high OS 0.92 (0.67–1.27) 0.92 0.67 1.27 Multivariate
       DFS 0.79 (0.61–1.02) 0.79 0.61 1.02  
Deng USA 2010 439 ≥10% low OS 1.27 (1.03–1.56) 1.27 1.03 1.56 NA
       DFS 1.77 (1.37–2.29) 1.77 1.37 2.29  
Landen USA 2010 65 > 1% low OS 1.39 (0.69–2.80) 1.39 0.69 2.8 Univariate
       DFS 2.03 (1.16–3.57) 2.03 1.16 3.57  
Wang China 2012 84 > 50% high OS 2.43 (1.12–5.28) 2.43 1.12 5.28 Multivariate
       DFS 1.70 (0.77–3.77) 1.7 0.77 3.77  
Liebscher Germany 2013 131 IRS ≥ 4 IRS OS 2.01 (1.03–3.93) 2.01 1.03 3.93 Multivariate
Kuroda Japan 2013a 62 > 20% high OS 1.63 (0.34–7.89) 1.63 0.34 7.89 Univariate
       DFS 1.95 (0.95–4.00) 1.95 0.95 4  
Kuroda Japan 2013b 37 > 15% low OS 3.62 (0.47–27.88) 3.62 0.47 27.88 Univariate
       DFS 3.97 (0.60–26.19) 3.97 0.6 26.19  
  1. HR Hazard ratio, CI confidence interval, OS overall survival, PFS progression-free survival, DFS disease free survival, IRS Infrequent restriction site, NA Not available