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Table 2 Comparison between the genotype and allele frequencies of rs1137101 in normal weight and obese PCOS patients and controls

From: The influence of the rs1137101 genotypes of leptin receptor gene on the demographic and metabolic profile of normal Saudi females and those suffering from polycystic ovarian syndrome

Genotype/allele

Control (N)

Control (O)

OR

CI

χ2

P-value

AA

42 (37.28)

40 (31.66)

Ref.

AG

13 (18.44)

10 (24.68)

0.76

0. 30-1.95

0.30

0.581

GG

5 (2.28)

12 (4.66)

2.40

0.77–7.44

2.39

0.122

AG + GG

18 (31.0)

22 (35.4)

1.22

0.57–2.61

0.27

0.605

A

93 (80.1)

90 (72.5)

Ref.

G

23 (19.8)

34 (27.4)

1.52

0.83–2.79

1.91

0.167

Genotype/allele

Patient (N)

Patient (O)

OR

CI

χ2

P-value

AA

42 (38.40)

43 (37.89)

Ref.

 

AG

12 (19.20)

17 (24.22)

1.38

0.59–3.24

0.56

0.454

GG

6 (2.40)

10 (4.89)

1.62

0.54–4.88

0.77

0.381

AG + GG

18 (30)

27 (38.5)

1.46

0.70–3.04

1.05

0.305

A

96 (80)

60 (42.8)

Ref.

 

G

24 (20)

27 (19.2)

1.43

0.80–2.57

1.49

0.222

Genotype/allele

Control (N)

Patient (N)

OR

CI

χ2

P-value

AA

42 (39.20)

42 (38.40)

Ref.

AG

13 (18.59)

12 (19.20)

0.92

0. 37-2.25

0.03

0.860

GG

2 (2.20)

6 (2.40)

1.20

0. 34-4.23

0.08

0.776

AG + GG

15 (25.8)

18 (29.0)

1.00

0.45–2.18

0.00

1.000

A

97 (83.6)

96 (80.0)

Ref.

G

15 (12.9)

24 (20.0)

1.05

0.55–1.99

0.03

0.870

Genotype/allele

Control (O)

Patient (O)

OR

CI

χ2

P-value

AA

40 (32.66)

43 (37.86)

Ref.

AG

10 (24.68)

17 (27.22)

1.58

0.64–3.85

1.02

0.311

GG

12 (4.66)

10 (4.89)

0.77

0. 30-1.99

0.28

0.596

AG + GG

22 (35.4)

27 (38.5)

1.14

0.56–2.31

0.13

0.714

A

90 (72.5)

103 (73.5)

Ref.

G

34 (27.4)

27 (19.2)

0.95

0.55–1.64

0.03

0.856