Cervical microbiota in women with cervical intra-epithelial neoplasia, prior to and after local excisional treatment, a Norwegian cohort study

Table 5 The cervical microbiota in the LEEP group and the Reference group

	LEEP group N = 89		Reference group N = 100		Unadjusted¹			Adjusted²
Bacteria	n	%	n	%	OR	CI	p	OR	CI	p
Bacteroides spp	7	8	0	0	∞		0.005	∞		0.008
Chlamydia trachomatis	3	3	1	1	3.5	0.4–33.8	0.34	2.3	0.2–26.0	0.52
Escherichia.coli	4	4	9	9	0.5	0.1–1.6	0.26	0.3	0.1–1.4	0.12
Gardnerella vaginalis	28	32	9	9	4.6	2.1–10.5	<.001	3.5	1.4–9.0	0.009
Mycoplasma hominis	17	19	3	3	7.6	2.2–27.0	0.001	2.4	0.6–9.5	0.21
Streptococcus spp	12	14	10	10	1.4	0.6–3.4	0.50	1.9	0.7–5.5	0.24
Ureaplasma parvum	41	46	16	16	4.5	2.3–8.8	<.001	3.9	1.6–9.3	0.002
Ureaplasma urealyticum	9	10	3	3	3.6	1.0–13.9	0.07	2.2	0.5–10.5	0.32
Lactobacillus spp	32	36	39	39	0.9	0.5–1.6	0.76	0.8	0.4–1.7	0.58
any non-Lactobacillus	59	66	41	41	2.8	1.6–5.1	0.001	2.2	1.1–4.5	0.03

¹Fisher’s exact test
²Logistic regression adjusted for Marital status, Hormonal Contraceptive Use, Smoking and Age. 188 cases analysed, 1 missing case in the reference group because of missing data on smoking
Abbreviations; CI Confidence Interval, LEEP Loop Electrosurgical Excisional Procedure, N numbers, OR Odds Ratio

ISSN: 1472-6874