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Table 3 Intra-laboratory reproducibility analysis by the cobas 6800 HPV assay. Overall (i.e., hrHPV positive/negative) and type-specific HPV test agreement were 99% (587/593 samples) and 98.3% (169/172 samples), respectively. Kappa value = 0.967 (95%CI 0.942–0.985)

From: HPV testing for cervical cancer screening: technical improvement of laboratory logistics and good clinical performance of the cobas 6800 in comparison to the 4800 system

Cobas 6800 HPV test results [1]

Cobas 6800 HPV test results [2]

Total

 

Positive

Negative

HPV16a

HPV18b

Other HPV

Negative

415

   

415

Positive

 HPV16a

2

49

 

1

52

 HPV18a,b

  

13

 

13

 Other HPV

4

 

2

107

113

Total

421

49

15

108

593

  1. asingle and mixed infections are included
  2. bHPV16/18 mixed infections are counted among HPV16-positives