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Table 1 Characteristics of included studies

From: Comparison of vaginal hysterectomy and laparoscopic hysterectomy: a systematic review and meta-analysis

First author, year Type of study Method Number of patients Inclusion criteria Exclusion criteria Outcomes Risk of bias according to Cochrane risk of bias tools
Agostini, 2006 RCT LAVH vs. VH 48 Benign uterine diseases, uterine size below pubis, favorable to BSO Adnexal mass Operative data, complications high
Allam, 2015 RCT TAH vs.TLH vs. VH 60 Benign uterine diseases Malignancy Operative data, complications unclear
Candiani, 2009 RCT TLH vs. VH 47 Benign uterine diseases Malignancy, estimated uterine volume > 300 mL, POP, ovarian pathology, PID§, endometriosis Operative data, complications high
Darai, 2001 RCT LAVH vs. VH 80 Estimated uterine size > 280 g, contraindications to VH Malignancy Operative data, complications high
Drahonovsky, 2010 RCT LAVH vs. TLH vs. VH 125 Benign uterine diseases Impossible VH, prior abdominal surgery, endometriosis, medical disorders Operative data, complications high
Eggemann, 2018 RCT LAVH vs. VH 192 Benign uterine diseases, possible VH Malignancy, POP, medical disorders Operative data, complications high
Garry, 2014 RCT Unspecified LH vs. VH 504 Benign uterine diseases Malignancy, POP, uterine size > 12 week gestation Operative data, complications high
Ghezzi, 2010 RCT TLH vs. VH 82 Benign uterine diseases Malignancy, POP, uterine size > 14 week gestation, large adnexal mass Operative data, complications high
Hwang, 2002 RCT LAVH, vs. TAH vs. VH 60 Myoma > 8 cm other benign gynecological conditions except myoma Operative data, complications high
Mohammed, 2017 RCT LAVH vs. VH 50 Benign uterine diseases, age (40–70 years), estimated uterine weight < 280 g BMI > 30, endometriosis, previous myomectomy, medical disorder Operative data, complications unclear
Ottosen, 2000 RCT LAVH vs. TAH vs. VH 80 Benign uterine disease, myoma < 15 cm Malignancy, uterine size > 16 week gestation, ovarian pathology, dense pelvic adhesion, possible VH Operative data, complications high
Ribeiro, 2003 RCT TAH vs. TLH vs. VH 40 Benign uterine diseases Estimated uterine volume > 400 cm3, medical disorders Operative data, complications, inflammatory response high
Roy, 2011 RCT LAVH vs. TLH vs. VH 90 Benign uterine diseases, estimated uterine weight < 400 g Malignancy, PID§, POP Operative data, complications high
Soriano, 2001 RCT LAVH vs. VH 77 Estimated uterine size > 280 g, contraindications to VH Malignancy Operative data, complications high
Sesti, 2014 RCT LAVH vs. TLH vs. VH 108 Symptomatic myoma, age < 55 years, uterine size > 12 week gestation Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, Operative data, complications low
Sesti, 2008 RCT LAVH vs. TLH vs. VH 100 Symptomatic myoma, age < 55 years, uterine size > 12 week gestation Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, Operative data, complication unclear
Sesti, 2008 RCT LAVH vs. VH 80 Symptomatic myoma, age < 55 years, uterine size > 12 week gestation Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, Operative data, complication unclear
Zhu, 2009 RCT LAVH vs. VH 69 Benign uterine diseases Malignancy Operative data, complication high
  1. † Bilateral salpingo-oophorectomy
  2. ‡ Pelvic organ prolapse
  3. § Pelvic inflammatory disease