Table 1 Characteristics of included studies
First author, year | Type of study | Method | Number of patients | Inclusion criteria | Exclusion criteria | Outcomes | Risk of bias according to Cochrane risk of bias tools |
|---|---|---|---|---|---|---|---|
Agostini, 2006 | RCT | LAVH vs. VH | 48 | Benign uterine diseases, uterine size below pubis, favorable to BSO† | Adnexal mass | Operative data, complications | high |
Allam, 2015 | RCT | TAH vs.TLH vs. VH | 60 | Benign uterine diseases | Malignancy | Operative data, complications | unclear |
Candiani, 2009 | RCT | TLH vs. VH | 47 | Benign uterine diseases | Malignancy, estimated uterine volume > 300 mL, POP‡, ovarian pathology, PID§, endometriosis | Operative data, complications | high |
Darai, 2001 | RCT | LAVH vs. VH | 80 | Estimated uterine size > 280 g, contraindications to VH | Malignancy | Operative data, complications | high |
Drahonovsky, 2010 | RCT | LAVH vs. TLH vs. VH | 125 | Benign uterine diseases | Impossible VH, prior abdominal surgery, endometriosis, medical disorders | Operative data, complications | high |
Eggemann, 2018 | RCT | LAVH vs. VH | 192 | Benign uterine diseases, possible VH | Malignancy, POP‡, medical disorders | Operative data, complications | high |
Garry, 2014 | RCT | Unspecified LH vs. VH | 504 | Benign uterine diseases | Malignancy, POP‡, uterine size > 12 week gestation | Operative data, complications | high |
Ghezzi, 2010 | RCT | TLH vs. VH | 82 | Benign uterine diseases | Malignancy, POP‡, uterine size > 14 week gestation, large adnexal mass | Operative data, complications | high |
Hwang, 2002 | RCT | LAVH, vs. TAH vs. VH | 60 | Myoma > 8 cm | other benign gynecological conditions except myoma | Operative data, complications | high |
Mohammed, 2017 | RCT | LAVH vs. VH | 50 | Benign uterine diseases, age (40–70 years), estimated uterine weight < 280 g | BMI > 30, endometriosis, previous myomectomy, medical disorder | Operative data, complications | unclear |
Ottosen, 2000 | RCT | LAVH vs. TAH vs. VH | 80 | Benign uterine disease, myoma < 15 cm | Malignancy, uterine size > 16 week gestation, ovarian pathology, dense pelvic adhesion, possible VH | Operative data, complications | high |
Ribeiro, 2003 | RCT | TAH vs. TLH vs. VH | 40 | Benign uterine diseases | Estimated uterine volume > 400 cm3, medical disorders | Operative data, complications, inflammatory response | high |
Roy, 2011 | RCT | LAVH vs. TLH vs. VH | 90 | Benign uterine diseases, estimated uterine weight < 400 g | Malignancy, PID§, POP‡ | Operative data, complications | high |
Soriano, 2001 | RCT | LAVH vs. VH | 77 | Estimated uterine size > 280 g, contraindications to VH | Malignancy | Operative data, complications | high |
Sesti, 2014 | RCT | LAVH vs. TLH vs. VH | 108 | Symptomatic myoma, age < 55 years, uterine size > 12 week gestation | Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, | Operative data, complications | low |
Sesti, 2008 | RCT | LAVH vs. TLH vs. VH | 100 | Symptomatic myoma, age < 55 years, uterine size > 12 week gestation | Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, | Operative data, complication | unclear |
Sesti, 2008 | RCT | LAVH vs. VH | 80 | Symptomatic myoma, age < 55 years, uterine size > 12 week gestation | Malignancy, nulliparity, uterine size > 16 week gestation, previous uterine surgery, | Operative data, complication | unclear |
Zhu, 2009 | RCT | LAVH vs. VH | 69 | Benign uterine diseases | Malignancy | Operative data, complication | high |